SCHEMBL4460159

SCHEMBL4460159

CCCCOCCOc1cc2c(cc1O)C1(CC2(C)C)CC(C)(C)c2cc(OCCOCCCC)c(O)cc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 7/20 0.38
RARB P10826 3/20 0.36
PPARG P37231 1/20 0.34
NR1H3 Q13133 1/20 0.34
DRD3 P35462 4/20 0.33
DRD1 P21728 3/20 0.33
OPRM1 P35372 1/20 0.33
HNF4A P41235 1/20 0.33
RARA P10276 1/20 0.33
ESR1 P03372 1/20 0.33
DRD2 P14416 2/20 0.32
SMPD1 P17405 1/20 0.32
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP1 P29466 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4469326 0.96 RXRA (0.38) RXRARARBPPARGNR1H3DRD3
SCHEMBL4474023 0.93 RXRA (0.41) RXRARARBPPARGNR1H3DRD3
SCHEMBL4464590 0.92 RXRA (0.41) RXRAPPARGNR1H3DRD3DRD1
SCHEMBL4467219 0.91 DRD1 (0.35) RXRAPPARGNR1H3DRD3DRD1
SCHEMBL4459350 0.89 DRD1 (0.36) RXRAPPARGNR1H3DRD3DRD1
SCHEMBL4460088 0.89 RXRA (0.43) RXRAPPARGNR1H3DRD3DRD1
SCHEMBL4461726 0.89 RXRA (0.43) RXRAPPARGNR1H3DRD3DRD1
SCHEMBL4463620 0.89 RXRA (0.43) RXRAPPARGNR1H3DRD3DRD1
SCHEMBL4474777 0.88 APP (0.36) RXRAPPARGNR1H3DRD3DRD1
SCHEMBL4462226 0.88 OPRM1 (0.40) RARBOPRM1RARAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7582355-B2 Optical unit using plastic lenses FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-20060046065-A1 Optical unit using plastic lenses FUJI PHOTO FILM CO., LTD. 2006-03-02 US disclosed
US-6028161-A EXCELLENT TRANSPARENCY, HEAT RESISTANCE AND MECHANICAL PROPERTIES AND A LOW BIREFRINGENCE, MELT FLUIDITY AND MOLDABILITY; AN OPTICAL DISK, LENS AND AN OPTICAL FIBER MITSUI CHEMICALS, INC. (JP) 2000-02-22 US disclosed
EP-0926180-A2 A polycarbonate copolymer and applications thereof Mitsui Chemicals, Inc. (JP) 1999-06-30 EP disclosed