Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3019212 | 0.74 | ALDH1A1 (0.46) | L3MBTL1MAPTLMNAHPGDALDH1A1 | |
| SCHEMBL23211131 | 0.74 | GAA (0.43) | L3MBTL1MAPTLMNAALDH1A1KMT2A | |
| SCHEMBL7255856 | 0.73 | GAA (0.41) | L3MBTL1MAPTLMNAHPGDALDH1A1 | |
| SCHEMBL6280529 | 0.73 | FBP1 (0.46) | L3MBTL1MAPTLMNAHPGDALDH1A1 | |
| SCHEMBL7258631 | 0.72 | GAA (0.40) | L3MBTL1MAPTLMNAHPGDALDH1A1 | |
| SCHEMBL7258606 | 0.72 | L3MBTL1 (0.40) | L3MBTL1MAPTLMNAHPGDALDH1A1 | |
| SCHEMBL27353569 | 0.71 | KMT2A (0.46) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL23496067 | 0.71 | KMT2A (0.55) | MAPTLMNAHPGDALDH1A1HSP90AA1 | |
| SCHEMBL15676131 | 0.71 | KMT2A (0.49) | MAPTLMNAHPGDALDH1A1HSP90AA1 | |
| SCHEMBL23496064 | 0.71 | KMT2A (0.55) | MAPTLMNAHPGDALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598232-B2 | Amino-substituted (E)-2,6-dialkoxystyryl 4-substituted-benzylsulfones for treating proliferative disorders | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2009-10-06 | — | — | US | disclosed |