SCHEMBL447598

SCHEMBL447598

CCC(CC)=C(C(N)=O)C(C)N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.36
GRIA4 P48058 1/20 0.36
GRIK3 Q13003 1/20 0.36
GRIK5 Q16478 1/20 0.36
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
LAP3 P28838 1/20 0.31
SLC15A1 P46059 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
GABRA1 P14867 2/20 0.30
GABRB1 P18505 2/20 0.30
GABRG2 P18507 2/20 0.30
GABRB3 P28472 2/20 0.30
GABRA5 P31644 2/20 0.30
GABRA3 P34903 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1072346 0.84 GRIK1 (0.39) GRIK1GRIA4GRIK3GRIK5CA1
SCHEMBL27301690 0.82 CES2 (0.35) CA1CA2SLC15A1GABRPGABRD
SCHEMBL18283238 0.81 GRIK1 (0.45) GRIK1GRIA4GRIK3GRIK5SLC1A3
SCHEMBL446932 0.72 LMNA (0.37) SLC7A5
Alanine SCHEMBL14157411 0.67 SLC7A5 (0.44) GRIK1GRIA4GRIK3GRIK5SLC1A3
Alanine SCHEMBL28256799 0.67 SLC7A5 (0.44) GRIK1GRIA4GRIK3GRIK5SLC1A3
SCHEMBL36268 0.67 SLC1A3 (0.35) GRIK1CA1CA2SLC1A3SLC1A2
SCHEMBL10067957 0.66
SCHEMBL1692225 0.66
SCHEMBL1727611 0.66 FFAR3 (0.44) GRIK1GRIA4GRIK3GRIK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3416626-B1 MICROSPHERES FOR USE IN THERAPEUTIC EMBOLIZATION BIOSPHERE MEDICAL INC (US) 2026-02-25 EP claimed
EP-4245782-B1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO BIOSPHERE MEDICAL INC (US) 2025-10-29 EP claimed
EP-4245782-A1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO BIOSPHERE MEDICAL, INC. (US) 2023-09-20 EP claimed
EP-3660061-B1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO BIOSPHERE MEDICAL INC (US) 2023-06-21 EP claimed
EP-3245236-B1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO BIOSPHERE MEDICAL INC (US) 2020-09-23 EP claimed
EP-3660061-A1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO BIOSPHERE MEDICAL, INC. (US) 2020-06-03 EP claimed
US-20190231908-A1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2019-08-01 US claimed
US-10265423-B2 Radiopaque monomers, polymers, microspheres, and methods related thereto BIOSPHERE MEDICAL, INC. (US) 2019-04-23 US claimed
EP-3245236-A1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO Biosphere Medical Inc. (US) 2017-11-22 EP claimed
CN-106420402-A Hair styling composition 九江天赐高新材料有限公司 2017-02-22 CN claimed
WO-2016115023-A1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO BIOSPHERE MEDICAL, INC. (US) 2016-07-21 WO claimed
US-20160200670-A1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO WELLS FARGO BANK, NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2016-07-14 US claimed
EP-1508042-A4 BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS BIO RAD LABORATORIES (US) 2008-04-02 EP claimed
EP-1508042-A2 BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS Ciphergen Biosystems, Inc. (US) 2005-02-23 EP claimed
US-20030218130-A1 Biochips with surfaces coated with polysaccharide-based hydrogels CIPHERGEN BIOSYSTEMS, INC. 2003-11-27 US claimed
WO-2003093785-A2 BIOCHIPS WITH SURFACES COATED WITH POLYSACCHARIDE BASED HYDROGELS CIPHERGEN BIOSYSTEMS, INC. (US) 2003-11-13 WO claimed
CN-1073467-A Pressure sensitive adhesive composition and use bonding of the pressure sensitive adhesive etc. of said composition LINTEC CORP (JP) 1993-06-23 CN claimed
US-4655934-A BASIC ALUMINUM HALIDE AS FLOCCULANTS TO CLARIFY WATER NALCO CHEMICAL COMPANY (US) 1987-04-07 US claimed
US-12540348-B2 Device and methods of using device for detection of aminoacidopathies UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2026-02-03 US disclosed
US-4588508-A CATIONIC HOMOPOLYMERS AND COPOLYMERS NALCO CEHMICAL COMPANY (US) 1986-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10265423-B2 Radiopaque monomers, polymers, microspheres, and methods related thereto CD68, MVD, RAD54L GRIK1 1457/4885GRIA4 3251/4885GRIK3 2029/4885
US-12540348-B2 Device and methods of using device for detection of aminoacidopathies DAO, UROD, ALAD GRIK1 2636/4885GRIA4 3884/4885GRIK3 3262/4885
US-20190231908-A1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO CD68, MVD, RAD54L GRIK1 1457/4885GRIA4 3251/4885GRIK3 2029/4885
US-20160200670-A1 RADIOPAQUE MONOMERS, POLYMERS, MICROSPHERES, AND METHODS RELATED THERETO CD68, MVD, RAD54L GRIK1 1457/4885GRIA4 3251/4885GRIK3 2029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.