Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4490618 | 0.91 | OPRL1 (0.57) | OPRL1MAPTMEN1KMT2AFLT1 | |
| SCHEMBL4490776 | 0.85 | OPRL1 (0.51) | OPRL1MAPTALDH1A1CHRNA7MALT1 | |
| SCHEMBL4492245 | 0.76 | OPRL1 (0.46) | OPRL1MAPTALDH1A1LMNACHRNA7 | |
| Hydrochloric Acid SCHEMBL4485649 | 0.72 | OPRL1 (0.52) | OPRL1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4491425 | 0.70 | FLT1 (0.47) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4564842 | 0.69 | OPRL1 (0.61) | OPRL1KMT2ACHRNA7 | |
| SCHEMBL2770695 | 0.68 | OPRL1 (0.56) | OPRL1MAPTMEN1KMT2AGAA | |
| SCHEMBL29668784 | 0.67 | TP53 (0.61) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL1946461 | 0.66 | MAPT (0.54) | MAPTMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL2540191 | 0.66 | CNR1 (0.50) | MAPTMEN1KMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524971-B2 | 1,5-diarylpyrrole derivatives, preparation method thereof and application of same in therapeutics | SANOFI - AVENTIS (FR) | 2009-04-28 | — | — | US | claimed |
| US-20080015245-A1 | 1,5-DIARYLPYRROLE DERIVATIVES, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2008-01-17 | — | — | US | claimed |
| US-7524971-B2 | 1,5-diarylpyrrole derivatives, preparation method thereof and application of same in therapeutics | SANOFI - AVENTIS (FR) | 2009-04-28 | — | — | US | disclosed |
| US-20080015245-A1 | 1,5-DIARYLPYRROLE DERIVATIVES, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015245-A1 | 1,5-DIARYLPYRROLE DERIVATIVES, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | QDPR, DPYD, CD38 | OPRL1 1286/4885MAPT 3797/4885MEN1 359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.