Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4476893 | 0.91 | OPRL1 (0.52) | OPRL1CHRNA7ALDH1A1MAPTPTGS2 | |
| SCHEMBL4490776 | 0.90 | OPRL1 (0.51) | OPRL1CHRNA7ALDH1A1NPC1MAPT | |
| Hydrochloric Acid SCHEMBL4564842 | 0.73 | OPRL1 (0.61) | OPRL1CHRNA7KMT2A | |
| SCHEMBL4492245 | 0.72 | OPRL1 (0.46) | OPRL1CHRNA7ALDH1A1MAPTPTGS2 | |
| SCHEMBL2903583 | 0.70 | RXFP1 (0.47) | ALDH1A1PKMHTR6HSD11B1CYP19A1 | |
| SCHEMBL4490567 | 0.69 | OPRL1 (0.49) | OPRL1ALDH1A1MAPTPTGS2KDR | |
| SCHEMBL4490242 | 0.67 | ALDH1A1 (0.42) | ALDH1A1NPC1MAPTPKMHSD11B1 | |
| SCHEMBL4465707 | 0.66 | NOTUM (0.63) | OPRL1CHRNA7ALDH1A1 | |
| SCHEMBL14434546 | 0.66 | ALDH1A1 (0.57) | ALDH1A1NPC1MAPTCYP19A1FLT1 | |
| SCHEMBL3013581 | 0.66 | CA12 (0.49) | OPRL1CHRNA7PTGS2FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524971-B2 | 1,5-diarylpyrrole derivatives, preparation method thereof and application of same in therapeutics | SANOFI - AVENTIS (FR) | 2009-04-28 | — | — | US | disclosed |
| US-20080015245-A1 | 1,5-DIARYLPYRROLE DERIVATIVES, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2008-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015245-A1 | 1,5-DIARYLPYRROLE DERIVATIVES, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | QDPR, DPYD, CD38 | OPRL1 1286/4885CHRNA7 3779/4885ALDH1A1 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.