Sulfuric Acid

Sulfuric Acid

SCHEMBL447772

O=S(=O)(O)Cl.O=S(=O)(O)O

nearest known ligand 0.67

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA5A P35218 2/20 0.67
CA5B Q9Y2D0 2/20 0.67
TSHR P16473 3/20 0.42
CA2 P00918 2/20 0.42
CA1 P00915 1/20 0.42
NT5E P21589 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
BLM P54132 2/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL27596127 0.95 CA5A (0.60) CA5ACA5BTSHRCA2CA1
Sulfuric Acid SCHEMBL6138634 0.95 CA5A (0.60) CA5ACA5BTSHRCA2CA1
SCHEMBL5517182 0.94 CA5A (0.56) CA5ACA5BTSHRCA2CA1
SCHEMBL82 0.94
SCHEMBL3128058 0.94
SCHEMBL4432240 0.94
SCHEMBL9124380 0.89
Phosphine SCHEMBL4043832 0.89
Water SCHEMBL2733257 0.89
Hydrochloric Acid SCHEMBL5057708 0.89 CA5A (0.50) CA5ACA5BTSHRCA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107648603-B Vaccine adjuvant, vaccine composition and application of sulfated chitosan oligosaccharide in preparation of vaccine adjuvant and vaccine composition 中国科学院过程工程研究所 2021-01-08 CN claimed
CN-107648603-A The purposes of vaccine adjuvant, vaccine combination and sulphation chitosan oligosaccharide in vaccine adjuvant and vaccine combination is prepared 中国科学院过程工程研究所 2018-02-02 CN claimed
CN-104109974-B Solvent Graft Method prepares ion-exchange fibre 北京服装学院 2016-09-28 CN claimed
EP-2025687-A1 Process for the preparation of heparanase-inhibiting sulfated hyaluronates and products obtained thereby Istituto Scientifico di Chimica E Biochimica "G Ronzoni (IT) 2009-02-18 EP claimed
CN-100460575-C Method for preparing ion exchange fiber by solution electrostatic spinning method BEIJING INST OF CLOTHING TECHN (CN) 2009-02-11 CN claimed
WO-2009013162-A1 PROCESS FOR THE PREPARATION OF HEPARANASE-INHIBITING SULFATED HYALURONATES AND PRODUCTS OBTAINED THEREBY ISTITUTO SCIENTIFICO DI CHIMICA E BIOCHIMICA 'G. RONZONI' (IT) 2009-01-29 WO claimed
CN-1936120-A Method for preparing ion exchange fiber by solution electrostatic spinning method BEIJNG GARMENT COLLEGE (CN) 2007-03-28 CN claimed
CN-1285412-C Making process of ion exchange fiber BEIJING INST OF CLOTHING TECHN (CN) 2006-11-22 CN claimed
CN-1608733-A Making process of ion exchange fiber BEIJING COSTUME COLLEGE (CN) 2005-04-27 CN claimed
US-5616622-A IMBIBING POLYMER SEEDS OF A VINYL AROMATIC COPOLYMER WITH A VINYL AROMATIC MONOMER(S) AND FREE RADICAL CATALYST; ADDITION POLYMERIZATION TO FORM A MATRIX; CROSSLINKING; ION EXCHANGE RESINS; OXIDATION RESISTANCE THE DOW CHEMICAL COMPANY (US) 1997-04-01 US claimed
EP-0340628-B1 Sulfoamino derivatives of chondroitin sulfates, of dermaten sulfate and of hyaluronic acid and their pharmacological properties CRINOS INDUSTRIA FARMACO (IT) 1994-07-27 EP claimed
US-4948881-A REACTING WITH MIXTURE OF SULFURIC ACID AND CHLOROSULFONIC ACID SANOFI (FR) 1990-08-14 US claimed
US-4727063-A ANTITHROMBOTIC, HYPERLIPEMIC, FIBRINOLYTIC ACTIVITY SCLAVO (IT) 1988-02-23 US claimed
JP-63049206-A None JP disclosed
CN-117487081-A Environment-friendly polymer composite multielement copolymerization filtrate reducer and preparation method thereof 四川盛年同缔实业有限公司 2024-02-02 CN disclosed
US-20230285907-A1 SINGLE PIECE-TYPE BIPOLAR FILM ROLL WITH MESH CLOTH SUPPORT AND MANUFACTURING METHOD THEREFOR QUZHOU LANRAN NEW MATERIAL CO., LTD. (CN) 2023-09-14 US disclosed
EP-0053815-A1 2-Oxoazetidine derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1982-06-16 EP disclosed
EP-0053387-A1 Method of preparing 1-sulfo-2-oxoazetidine derivatives and intermediates therefor Takeda Chemical Industries, Ltd. (JP) 1982-06-09 EP disclosed
EP-0050965-A1 Beta-lactamase inhibitory composition Takeda Chemical Industries, Ltd. (JP) 1982-05-05 EP disclosed
US-4177331-A SULFONATION OR CHLOROSULFONATION ROHM AND HAAS COMPANY (US) 1979-12-04 US disclosed