Sulfuric Acid

Sulfuric Acid

SCHEMBL6138634

O=S(=O)(O)Cl.O=S(=O)(O)O.[B]

nearest known ligand 0.60

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA5A P35218 2/20 0.60
CA5B Q9Y2D0 2/20 0.60
TSHR P16473 3/20 0.39
CA2 P00918 2/20 0.39
CA1 P00915 1/20 0.39
NT5E P21589 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
BLM P54132 2/20 0.38
KDM4E B2RXH2 2/20 0.38
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL447772 0.95 CA5A (0.67) CA5ACA5BTSHRCA2CA1
Sulfuric Acid SCHEMBL27596127 0.90 CA5A (0.60) CA5ACA5BTSHRCA2CA1
SCHEMBL3128058 0.89
SCHEMBL5517182 0.89 CA5A (0.56) CA5ACA5BTSHRCA2CA1
SCHEMBL4432240 0.89
SCHEMBL82 0.89
SCHEMBL9124380 0.84
Water SCHEMBL2733257 0.84
SCHEMBL4043838 0.84
Hydrochloric Acid SCHEMBL5057708 0.84 CA5A (0.50) CA5ACA5BTSHRCA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1275695-C High-productivity bisphenol A catalyst ROHM & HAAS (US) 2006-09-20 CN disclosed
EP-1222960-B1 Process for the preparation of bisphenol-A using a catalyst based on a sulfonated polystyrene/divinylbenzene copolymer ROHM & HAAS (US) 2005-08-17 EP disclosed
US-20040181100-A1 High productivity bisphenol-a-catalyst LUNDQUIST ERIC GUSTAVE (US) 2004-09-16 US disclosed
US-6730816-B2 STRONGLY ACIDIC CATION-EXCHANGE RESIN SPHERES OF A DIVINYLBENZENE-STYRENE COPOLYMER SULFONATED TO PRODUCE CROSSLINKING; DIMENSIONAL STABILITY; REACTING PHENOL AND ACETONE IN A CYLINDRICAL FIXED-BED REACTOR FILLED WITH BEADS ROHM AND HAAS COMPANY 2004-05-04 US disclosed
US-20020123534-A1 High productivity bisphenol-a catalyst ROHM AND HAAS COMPANY 2002-09-05 US disclosed
CN-1362291-A High-productivity bisphenol A catalyst ROHM & HAAS (US) 2002-08-07 CN disclosed
EP-1222960-A2 Bisphenol-A catalyst based on a sulfonated polystyrene/divinylbenzene copolymer ROHM AND HAAS COMPANY (US) 2002-07-17 EP disclosed