SCHEMBL4478616

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4477905	0.88	CNR2 (0.47)	CNR2MLNRKCNJ1CYP1A2CYP2C19
	SCHEMBL4476032	0.84	CNR2 (0.66)	CNR2LTA4HHSD11B1KDM4EALDH1A1
	SCHEMBL4481553	0.80	CNR2 (0.73)	CNR2
	SCHEMBL4481560	0.80	CNR2 (0.73)	CNR2
	SCHEMBL4482468	0.77	TRPV6 (0.54)	CNR2KCNJ1LTA4H
	SCHEMBL4480091	0.75	LTA4H (0.44)	CNR2KCNJ1LTA4HALDH1A1
	SCHEMBL6698689	0.74	TACR1 (0.55)	CYP1A2CYP2C19
	SCHEMBL3272922	0.74	SIGMAR1 (0.54)	CYP1A2CYP2C19LTA4HALDH1A1
	SCHEMBL3277741	0.74	SIGMAR1 (0.54)	CYP1A2CYP2C19LTA4HALDH1A1
	SCHEMBL3272931	0.74	SIGMAR1 (0.54)	CYP1A2CYP2C19LTA4HALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.