Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40135 | 1.00 | TSHR (0.34) | TSHRALDH1A1MAPK1SMN1; SMN2BCHE | |
| SCHEMBL15070155 | 0.87 | RCE1 (0.36) | TSHRALDH1A1MAPK1SMN1; SMN2BCHE | |
| SCHEMBL44573 | 0.82 | SMN1; SMN2 (0.36) | TSHRALDH1A1SMN1; SMN2ADRA2BADRA2C | |
| SCHEMBL44025 | 0.81 | TSHR (0.41) | TSHRALDH1A1MAPK1SMN1; SMN2BCHE | |
| SCHEMBL45416 | 0.79 | SIGMAR1 (0.46) | TSHRALDH1A1SMN1; SMN2ADRA2BADRA2C | |
| SCHEMBL38834 | 0.73 | BCHE (0.34) | TSHRALDH1A1MAPK1SMN1; SMN2BCHE | |
| SCHEMBL44484 | 0.73 | CSNK1E (0.41) | BCHEKCNH2SIGMAR1 | |
| SCHEMBL44989 | 0.71 | SIGMAR1 (0.41) | TSHRALDH1A1MAPK1SMN1; SMN2BCHE | |
| SCHEMBL3331448 | 0.71 | SIGMAR1 (0.44) | TSHRALDH1A1MAPK1SMN1; SMN2BCHE | |
| SCHEMBL15070151 | 0.70 | SIGMAR1 (0.41) | TSHRALDH1A1MAPK1SMN1; SMN2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079824-B2 | Method for the synthesis of an amino acetal | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-07-14 | — | — | US | disclosed |
| US-20130165682-A1 | METHOD FOR THE SYNTHESIS OF AN AMINO ACETAL | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-06-27 | — | — | US | disclosed |
| WO-2012005693-A1 | METHOD FOR THE SYNTHESIS OF AN AMINO ACETAL | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165682-A1 | METHOD FOR THE SYNTHESIS OF AN AMINO ACETAL | AOX1, DAO, ALDH7A1 | TSHR 3830/4885ALDH1A1 11/4885MAPK1 3535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.