Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44025 | 0.87 | TSHR (0.41) | SIGMAR1SLC6A2SLC6A3SLC6A4ADRA2B | |
| SCHEMBL15070157 | 0.86 | SIGMAR1 (0.47) | SIGMAR1SLC6A2SLC6A3SLC6A4ADRA2B | |
| SCHEMBL44573 | 0.82 | SMN1; SMN2 (0.36) | SIGMAR1SLC6A2SLC6A3SLC6A4ADRA2B | |
| SCHEMBL44989 | 0.80 | SIGMAR1 (0.41) | SIGMAR1SLC6A2SLC6A3SLC6A4ADRA2B | |
| SCHEMBL3331448 | 0.79 | SIGMAR1 (0.44) | SIGMAR1SLC6A2SLC6A3SLC6A4ADRA2B | |
| SCHEMBL44484 | 0.79 | CSNK1E (0.41) | SIGMAR1KCNH2 | |
| SCHEMBL40135 | 0.79 | TSHR (0.34) | SIGMAR1SLC6A2SLC6A3SLC6A4ADRA2B | |
| SCHEMBL44789 | 0.79 | TSHR (0.34) | SIGMAR1SLC6A2SLC6A3SLC6A4ADRA2B | |
| SCHEMBL9328423 | 0.78 | SIGMAR1 (0.50) | SIGMAR1SLC6A2SLC6A3SLC6A4ADRA2B | |
| SCHEMBL40060 | 0.77 | KDM4E (0.43) | ALDH1A1KDM4EMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079824-B2 | Method for the synthesis of an amino acetal | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-07-14 | — | — | US | disclosed |
| US-20130165682-A1 | METHOD FOR THE SYNTHESIS OF AN AMINO ACETAL | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-06-27 | — | — | US | disclosed |
| WO-2012005693-A1 | METHOD FOR THE SYNTHESIS OF AN AMINO ACETAL | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-01-12 | — | — | WO | disclosed |
| WO-2012005693-A1 | METHOD FOR THE SYNTHESIS OF AN AMINO ACETAL | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165682-A1 | METHOD FOR THE SYNTHESIS OF AN AMINO ACETAL | AOX1, DAO, ALDH7A1 | SIGMAR1 1259/4885SLC6A2 3038/4885SLC6A3 2513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.