Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL4479018

N.O=C(O)Cc1ccccc1F

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CXCL8 P10145 2/20 0.62
AKR1B1 P15121 2/20 0.59
TDP1 Q9NUW8 1/20 0.52
ALDH1A1 P00352 4/20 0.51
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
LMNA P02545 1/20 0.50
RAB9A P51151 1/20 0.50
PTGS2 P35354 2/20 0.49
MAPK1 P28482 1/20 0.49
KDM4E B2RXH2 1/20 0.46
PTGS1 P23219 1/20 0.46
BCAT2 O15382 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29533621 0.98 CXCL8 (0.65) CXCL8AKR1B1TDP1ALDH1A1MEN1
SCHEMBL8645 0.98 CXCL8 (0.65) CXCL8AKR1B1TDP1ALDH1A1MEN1
Fluoride SCHEMBL11183201 0.96 CXCL8 (0.62) CXCL8AKR1B1TDP1ALDH1A1MEN1
Hydrochloric Acid SCHEMBL1371542 0.96 CXCL8 (0.62) CXCL8AKR1B1TDP1ALDH1A1MEN1
SCHEMBL6969660 0.82 ALDH1A1 (0.51) CXCL8ALDH1A1MEN1KMT2ALMNA
SCHEMBL4661911 0.82 ALDH1A1 (0.51) CXCL8ALDH1A1MEN1KMT2ALMNA
SCHEMBL8209127 0.82 CXCL8 (0.53) CXCL8AKR1B1ALDH1A1MEN1KMT2A
SCHEMBL538984 0.82 CXCL8 (0.57) CXCL8AKR1B1TDP1ALDH1A1MEN1
SCHEMBL27856925 0.81 CXCL8 (0.53) CXCL8AKR1B1TDP1ALDH1A1MEN1
SCHEMBL29410826 0.81 AKR1B1 (0.76) CXCL8AKR1B1TDP1LMNAPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1731534-B1 Aqueous dispersion of polytetrafluorethylene ASAHI GLASS CO LTD (JP) 2014-07-02 EP claimed
US-7514484-B2 Aqueous dispersion of polytetrafluoroethylene and process for its production ASAHI GLASS COMPANY, LIMITED (JP) 2009-04-07 US claimed
EP-1731534-A1 Aqueous dispersion of polytetrafluorethylene and process for its production Asahi Glass Company, Limited (JP) 2006-12-13 EP claimed
US-20060276574-A1 Aqueous dispersion of polytetrafluoroethylene and process for its production ASAHI GLASS COMPANY, LIMITED (JP) 2006-12-07 US claimed
EP-1731534-B1 Aqueous dispersion of polytetrafluorethylene ASAHI GLASS CO LTD (JP) 2014-07-02 EP disclosed
US-7514484-B2 Aqueous dispersion of polytetrafluoroethylene and process for its production ASAHI GLASS COMPANY, LIMITED (JP) 2009-04-07 US disclosed
EP-1731534-A1 Aqueous dispersion of polytetrafluorethylene and process for its production Asahi Glass Company, Limited (JP) 2006-12-13 EP disclosed
US-20060276574-A1 Aqueous dispersion of polytetrafluoroethylene and process for its production ASAHI GLASS COMPANY, LIMITED (JP) 2006-12-07 US disclosed