⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8709145 | 0.65 | — | — | |
| SCHEMBL47206 | 0.65 | — | — | |
| SCHEMBL14764888 | 0.63 | — | — | |
| SCHEMBL7442697 | 0.63 | — | — | |
| SCHEMBL472353 | 0.63 | NOTUM (1.00) | — | |
| SCHEMBL2008205 | 0.62 | — | — | |
| SCHEMBL448147 | 0.62 | — | — | |
| SCHEMBL10768177 | 0.59 | PKM (0.78) | — | |
| SCHEMBL682505 | 0.59 | — | — | |
| SCHEMBL450319 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | SIGNALRX PHARMACEUTICALS, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| US-11760762-B2 | Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors | SIGNALRX PHARMACEUTICALS, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| CN-115108979-B | Preparation method of 8-hydroxyquinoline derivative | 江苏海洋大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-111362966-B | Bicyclic heterocyclic derivatives as IRAK4 inhibitors | 奥列基因发现技术有限公司 | 2022-03-11 | — | — | CN | disclosed |
| US-20210186021-A1 | DIAMINOTRIAZINE COMPOUNDS | BASF SE (DE) | 2021-06-24 | — | — | US | disclosed |
| WO-2021063735-A1 | NEW BICYCLIC PYRIDINE DERIVATIVES | BASF SE (DE) | 2021-04-08 | — | — | WO | disclosed |
| CN-111362966-A | Bicyclic heterocyclic derivatives as IRAK4 inhibitors | 奥列基因发现技术有限公司 | 2020-07-03 | — | — | CN | disclosed |
| CN-106456619-B | Bicyclic heterocyclic derivatives as IRAK4 inhibitors | 奥列基因发现技术有限公司 | 2020-03-27 | — | — | CN | disclosed |
| EP-2997824-A1 | NOVEL HERBICIDES | Syngenta Participations AG. (CH) | 2016-03-23 | — | — | EP | disclosed |
| EP-2375898-B1 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-16 | — | — | EP | disclosed |
| US-8889595-B2 | Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2014-11-18 | — | — | US | disclosed |
| US-20120065064-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-03-15 | — | — | US | disclosed |
| CN-102300458-A | New herbicides | — | 2011-12-28 | — | — | CN | disclosed |