Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9297488 | 0.79 | ALDH1A1 (0.41) | IDO1TDO2PPARGPPARATSHR | |
| SCHEMBL9298647 | 0.79 | IDO1 (0.44) | IDO1TDO2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4480102 | 0.77 | SLC6A2 (0.53) | IDO1TDO2ESR1TSHRHTR2A | |
| SCHEMBL12841456 | 0.77 | NOS2 (0.50) | TSHRHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL6823348 | 0.77 | NOS2 (0.50) | TSHRHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL6823741 | 0.76 | SLC6A2 (0.41) | ESR2TYRPPARGPPARATSHR | |
| SCHEMBL3716834 | 0.76 | HTR2B (0.42) | ESR2ESR1TSHRHTR2AHTR2C | |
| SCHEMBL8082370 | 0.75 | SLC6A4 (0.71) | TSHRHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL4623634 | 0.75 | SLC6A4 (0.71) | TSHRHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL30501482 | 0.75 | SLC6A4 (0.71) | TSHRHTR2AHTR2CHTR2BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446722-A1 | Novel hydroxylated phenoxy compounds and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | claimed |
| EP-0446722-A1 | Novel hydroxylated phenoxy compounds and process for their preparation | Bromine Compounds Ltd. (IL) | 1991-09-18 | — | — | EP | disclosed |