SCHEMBL4480340

SCHEMBL4480340

N[C@@H](CCCCNC(=O)CCCS)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OTC P00480 1/20 0.53
NOD1 Q9Y239 4/20 0.51
TDP1 Q9NUW8 1/20 0.48
GSR P00390 2/20 0.46
FNTA P49354 2/20 0.42
FNTB P49356 2/20 0.42
PGGT1B P53609 1/20 0.42
ARG2 P78540 4/20 0.42
ARG1 P05089 3/20 0.42
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19733064 1.00 OTC (0.53) OTCNOD1TDP1GSRFNTA
SCHEMBL18643429 0.92 OTC (0.54) OTCNOD1TDP1GSRFNTA
SCHEMBL9922798 0.92 OTC (0.54) OTCNOD1TDP1GSRFNTA
SCHEMBL12801715 0.92 OTC (0.54) OTCNOD1TDP1GSRFNTA
SCHEMBL41534 0.87 NOD1 (0.49) OTCNOD1TDP1GSRFNTA
SCHEMBL18656205 0.87 OTC (0.59) OTCNOD1TDP1GSRARG2
SCHEMBL10005285 0.86 OTC (0.58) OTCNOD1TDP1GSRARG2
SCHEMBL365299 0.86 OTC (0.58) OTCNOD1TDP1GSRARG2
SCHEMBL29486962 0.86 OTC (0.58) OTCNOD1TDP1GSRARG2
SCHEMBL13611057 0.85 NOD1 (0.56) OTCNOD1TDP1GSRGRM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1753803-B1 POLYPEPTIDES WITH THE CAPACITY TO ENTRAP DRUGS AND RELEASE THEM IN A CONTROLLED WAY FARMHISPANIA (ES) 2009-04-08 EP claimed
EP-1753803-A2 POLYPEPTIDES WITH THE CAPACITY TO ENTRAP DRUGS AND RELEASE THEM IN A CONTROLLED WAY Farmhispania S.A. (ES) 2007-02-21 EP claimed
WO-2005121215-A2 POLYPEPTIDES WITH THE CAPACITY TO ENTRAP DRUGS AND RELEASE THEM IN A CONTROLLED WAY FARMHISPANIA, S.A. (ES) 2005-12-22 WO claimed
US-20050276783-A1 Polypeptides with the capacity to entrap drugs and release them in a controlled way FARMHISPANIA, S.A. (ES) 2005-12-15 US claimed
EP-2102267-A2 POLYPEPTIDES WITH THE CAPACITY TO ENTRAP DRUGS Farmhispania S.A. (ES) 2009-09-23 EP disclosed
EP-1753803-B1 POLYPEPTIDES WITH THE CAPACITY TO ENTRAP DRUGS AND RELEASE THEM IN A CONTROLLED WAY FARMHISPANIA (ES) 2009-04-08 EP disclosed
WO-2008071594-A2 POLYPEPTIDES WITH THE CAPACITY TO ENTRAP DRUGS FARMHISPANIA S.A. (ES) 2008-06-19 WO disclosed
US-20070134335-A1 POLYPEPTIDES WITH THE CAPACITY TO ENTRAP DRUGS AND RELEASE THEM IN A CONTROLLED WAY FARMHISPANIA S.A. (ES) 2007-06-14 US disclosed
EP-1753803-A2 POLYPEPTIDES WITH THE CAPACITY TO ENTRAP DRUGS AND RELEASE THEM IN A CONTROLLED WAY Farmhispania S.A. (ES) 2007-02-21 EP disclosed
WO-2005121215-A2 POLYPEPTIDES WITH THE CAPACITY TO ENTRAP DRUGS AND RELEASE THEM IN A CONTROLLED WAY FARMHISPANIA, S.A. (ES) 2005-12-22 WO disclosed
US-20050276783-A1 Polypeptides with the capacity to entrap drugs and release them in a controlled way FARMHISPANIA, S.A. (ES) 2005-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070134335-A1 POLYPEPTIDES WITH THE CAPACITY TO ENTRAP DRUGS AND RELEASE THEM IN A CONTROLLED WAY DNPEP, LNPEP, PTMS OTC 1392/4885NOD1 3803/4885TDP1 2519/4885
US-20050276783-A1 Polypeptides with the capacity to entrap drugs and release them in a controlled way DNPEP, LNPEP, PTMS OTC 1392/4885NOD1 3803/4885TDP1 2519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.