Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023012 | 0.93 | GPR119 (0.53) | GPR119KDM4EPKMFAAHPOLB | |
| SCHEMBL4476300 | 0.87 | GPR119 (0.48) | GPR119USP30 | |
| SCHEMBL4768721 | 0.83 | GPR119 (0.62) | GPR119KDM4EPKMPOLBUSP30 | |
| SCHEMBL4248138 | 0.82 | KDM4E (0.60) | GPR119KDM4EPKMGAATHRB | |
| SCHEMBL4473405 | 0.82 | FAAH (0.53) | GPR119KDM4EPKMFAAH | |
| SCHEMBL4475396 | 0.82 | POLB (0.54) | PKMPOLBGAASMN1; SMN2 | |
| SCHEMBL17948871 | 0.81 | POLB (0.56) | GPR119KDM4EPKMFAAHPOLB | |
| SCHEMBL15593393 | 0.81 | GPR119 (0.46) | GPR119POLBUSP30 | |
| SCHEMBL13627221 | 0.80 | GPR119 (0.51) | GPR119KDM4EPKMFAAHUSP30 | |
| SCHEMBL1088570 | 0.80 | GPR119 (0.61) | GPR119KDM4EPKMFAAHPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7494992-B2 | Antiparasitic terpene alkaloids | PFIZER INC. (US) | 2009-02-24 | — | — | US | disclosed |
| US-20070185101-A1 | Antiparasitic terpene alkaloids | PFIZER PRODUCTS INC | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185101-A1 | Antiparasitic terpene alkaloids | CYP51A1, DHPS, CYP8B1 | GPR119 1945/4885KDM4E 752/4885PKM 3659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.