Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4499139 | 0.80 | GPR3 (0.32) | — | |
| Hydrochloric Acid SCHEMBL4499506 | 0.77 | ACHE (0.31) | — | |
| Hydrochloric Acid SCHEMBL715077 | 0.71 | DPP4 (0.37) | MEN1POLBKMT2AATM | |
| Hydrochloric Acid SCHEMBL3271901 | 0.71 | MEN1 (0.30) | MEN1POLBKMT2AATM | |
| Hydrochloric Acid SCHEMBL396286 | 0.70 | GPR3 (0.33) | — | |
| SCHEMBL7697621 | 0.69 | MEN1 (0.31) | MEN1POLBKMT2AATM | |
| Hydrochloric Acid SCHEMBL9068886 | 0.66 | — | — | |
| Ethane SCHEMBL8633225 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL674280 | 0.65 | — | — | |
| Fluoride SCHEMBL7637221 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716185-B1 | Titanocene-based catalyst system | STICHTING DUTCH POLYMER INST (NL) | 2009-10-21 | — | — | EP | disclosed |
| US-20080234452-A1 | TITANOCENE-BASED CATALYST SYSTEM | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2008-09-25 | — | — | US | disclosed |
| US-20070179049-A1 | Titanocenen-based catalyst system | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2007-08-02 | — | — | US | disclosed |
| EP-1716185-A1 | TITANOCENE-BASED CATALYST SYSTEM | Stichting Dutch Polymer Institute (NL) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005077989-A1 | TITANOCENEN-BASED CATALYST SYSTEM | STICHTING DUTCH POLYMER INSTITUTE (NL) | 2005-08-25 | — | — | WO | disclosed |
| EP-1564226-A1 | Titanocene-based catalyst system | Stichting Dutch Polymer Institute (NL) | 2005-08-17 | — | — | EP | disclosed |