Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | C1R | P00736 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11963991 | 0.72 | NOTUM (0.44) | NOTUMNPC1RAB9AALDH1A1PTPN1 | |
| SCHEMBL40959 | 0.72 | GAA (0.48) | NOTUMNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL14373829 | 0.70 | NOTUM (0.62) | PDCD1CD274NOTUMNPC1RAB9A | |
| SCHEMBL20267436 | 0.70 | ALDH1A1 (0.43) | CRBNPDCD1CD274NPC1CA12 | |
| SCHEMBL4763654 | 0.70 | ALDH1A1 (0.47) | CRBNPDCD1CD274NPC1RAB9A | |
| SCHEMBL11963997 | 0.70 | NOTUM (0.41) | NOTUMNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL181974 | 0.70 | NOTUM (0.67) | PDCD1CD274NOTUMNPC1RAB9A | |
| SCHEMBL18228978 | 0.67 | ALDH1A1 (0.50) | C1RCA12RAB9AALDH1A1KMT2A | |
| SCHEMBL29788337 | 0.67 | CA1 (0.71) | CA12RAB9AALDH1A1METAP2KMT2A | |
| SCHEMBL301996 | 0.67 | CA1 (0.71) | CA12RAB9AALDH1A1METAP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065063-A1 | 3-Aryl-4-(2,6-dimethylbenzylidene)isoxazol-5(4H)-ones as Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-03-15 | — | — | US | disclosed |
| WO-2011161034-A1 | 3-ARYL-4-(2,6-DIMETHYLBENZYLIDENE)-ISOXAZOL-5(4H)-ONES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065063-A1 | 3-Aryl-4-(2,6-dimethylbenzylidene)isoxazol-5(4H)-ones as Fungicides | CYP4X1, CYP4Z1, HAAO | CRBN 158/4885PDCD1 1209/4885CD274 1697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.