SCHEMBL4482218

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4482389	0.89	CDK2 (0.43)	ALDH1A1HTTMAPTSMN1; SMN2MTNR1A
	SCHEMBL4488036	0.87	TACR3 (0.51)	MAPTSMN1; SMN2GAATP53KDM4E
	SCHEMBL4497855	0.84	PTGDR (0.51)	ALDH1A1MAPTPOLBSMN1; SMN2HPGD
	SCHEMBL4493553	0.83	KMT2A (0.57)	ALDH1A1MAPK1MAPTPOLBSMN1; SMN2
	SCHEMBL4487805	0.83	NFKB1 (0.48)	MAPTSMN1; SMN2TP53CYP3A4MEN1
	SCHEMBL4492686	0.83	CSNK2A2 (0.55)	ALDH1A1MAPTMTNR1AMTNR1BAKR1C3
	SCHEMBL4495043	0.82	SLC16A3 (0.46)	ALDH1A1MAPTPOLBSMN1; SMN2HPGD
	SCHEMBL4487682	0.82	ALDH1A1 (0.49)	ALDH1A1HTTMAPTPOLBSMN1; SMN2
	SCHEMBL4489484	0.81	TDP1 (0.50)	ALDH1A1HTTMAPTPOLBSMN1; SMN2
	SCHEMBL4481447	0.81	FERMT2 (0.45)	ALDH1A1MAPTPOLBSMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.