Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4490394 | 0.85 | — | — | |
| SCHEMBL4504364 | 0.83 | — | — | |
| SCHEMBL4489152 | 0.81 | TDP1 (0.44) | ATMTDP1L3MBTL1 | |
| SCHEMBL4485724 | 0.76 | FFAR1 (0.37) | ATMTDP1L3MBTL1 | |
| SCHEMBL4495534 | 0.76 | GRM5 (0.39) | — | |
| SCHEMBL4504858 | 0.73 | PYCR1 (0.39) | — | |
| SCHEMBL4505670 | 0.72 | — | — | |
| SCHEMBL4494936 | 0.72 | — | — | |
| SCHEMBL4505398 | 0.72 | — | — | |
| SCHEMBL4491009 | 0.72 | ALDH1A1 (0.43) | ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |