Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4498679 | 0.87 | CCNC (0.36) | ALDH1A1HPGDPOLBKDM4ELMNA | |
| SCHEMBL4490745 | 0.87 | GRIA2 (0.40) | ALDH1A1KDM4EL3MBTL1HSD17B10DHODH | |
| SCHEMBL4488870 | 0.85 | MEN1 (0.43) | ALDH1A1KDM4ELMNASMN1; SMN2MAPT | |
| SCHEMBL4491745 | 0.83 | AR (0.43) | ALDH1A1POLBKDM4EMAPTRAB9A | |
| SCHEMBL4495477 | 0.83 | ALDH1A1 (0.42) | ALDH1A1HPGDKDM4EHTTMAPT | |
| SCHEMBL4495795 | 0.82 | ERN1 (0.46) | ALDH1A1HPGDPOLBL3MBTL1 | |
| SCHEMBL4494579 | 0.81 | ALDH1A1 (0.43) | ALDH1A1HPGDPOLBKDM4ELMNA | |
| SCHEMBL4492957 | 0.80 | GRIA2 (0.42) | ALDH1A1HPGDKDM4ENPC1MAPT | |
| SCHEMBL2215150 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HPGDPOLBKDM4ELMNA | |
| SCHEMBL4488653 | 0.80 | ERCC1 (0.38) | ALDH1A1HPGDPOLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |