Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3949713 | 0.81 | MEN1 (0.36) | TLR8TLR7RAB9ANPC1CYP1A2 | |
| SCHEMBL7218646 | 0.79 | KDM4E (0.47) | RAB9ANPC1CYP1A2CYP2C19MCL1 | |
| SCHEMBL30665024 | 0.78 | MEN1 (0.39) | TLR8TLR7GCGRRAB9ANPC1 | |
| SCHEMBL30665022 | 0.74 | KCNH2 (0.38) | TLR8TLR7RAB9ANPC1CYP1A2 | |
| SCHEMBL6504654 | 0.71 | — | — | |
| SCHEMBL13566391 | 0.71 | KCNH2 (0.38) | TLR8TLR7KMT2AMEN1ALDH1A1 | |
| SCHEMBL532911 | 0.71 | MEN1 (0.36) | TLR8TLR7RAB9ANPC1CYP1A2 | |
| SCHEMBL4482725 | 0.67 | PTPN1 (0.34) | — | |
| SCHEMBL2616804 | 0.66 | TLR8 (0.33) | TLR8TLR7KMT2AMEN1 | |
| SCHEMBL5008313 | 0.66 | MEN1 (0.37) | TLR8TLR7RAB9ANPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101092415-A | Compound of new benzo heterocycle categories, preparation method and application | SHANGHAI INST OF MEDICINES C A (CN) | 2007-12-26 | — | — | CN | claimed |
| CN-1810795-A | Benzopyran compound and its prepn and use | SHANGHAI INST OF MEDICAMENTS C (CN) | 2006-08-02 | — | — | CN | claimed |
| CN-101092415-B | Compound of new benzo heterocycle categories, preparation method and application | SHANGHAI INST MATERIA MEDICA | 2011-04-27 | — | — | CN | disclosed |
| US-7557123-B2 | Heterocyclic compound and medicinal use thereof | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2009-07-07 | — | — | US | disclosed |
| CN-101092415-A | Compound of new benzo heterocycle categories, preparation method and application | SHANGHAI INST OF MEDICINES C A (CN) | 2007-12-26 | — | — | CN | disclosed |
| CN-1810795-A | Benzopyran compound and its prepn and use | SHANGHAI INST OF MEDICAMENTS C (CN) | 2006-08-02 | — | — | CN | disclosed |
| US-20040220215-A1 | Novel heterocyclic compound and medicinal use thereof | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2004-11-04 | — | — | US | disclosed |
| EP-1403253-A1 | NOVEL HETEROCYCLIC COMPOUND AND MEDICINAL USE THEREOF | Kyoto Pharmaceutical Industries, Ltd. (JP) | 2004-03-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220215-A1 | Novel heterocyclic compound and medicinal use thereof | GPR119, INSR, GLP1R | TLR8 171/4885TLR7 148/4885GCGR 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.