Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483688 | 1.00 | P2RX7 (0.47) | P2RX7GPR119CTSKL3MBTL1HSD11B1 | |
| SCHEMBL4483683 | 1.00 | P2RX7 (0.47) | P2RX7GPR119CTSKL3MBTL1HSD11B1 | |
| SCHEMBL5444431 | 0.86 | PDE4B (0.51) | P2RX7GPR119CTSKL3MBTL1HSD11B1 | |
| SCHEMBL5225674 | 0.86 | PDE4B (0.51) | P2RX7GPR119CTSKL3MBTL1HSD11B1 | |
| SCHEMBL5444435 | 0.86 | PDE4B (0.51) | P2RX7GPR119CTSKL3MBTL1HSD11B1 | |
| SCHEMBL4483103 | 0.85 | CTSK (0.46) | CTSKHSD11B1MEN1KMT2ADPP4 | |
| SCHEMBL30368828 | 0.83 | USP30 (0.52) | GPR119CTSKL3MBTL1HSD11B1DPP4 | |
| SCHEMBL15409022 | 0.83 | USP30 (0.52) | GPR119CTSKL3MBTL1HSD11B1DPP4 | |
| SCHEMBL3332405 | 0.83 | USP30 (0.52) | GPR119CTSKL3MBTL1HSD11B1DPP4 | |
| SCHEMBL3332409 | 0.83 | USP30 (0.52) | GPR119CTSKL3MBTL1HSD11B1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |