Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | DPP4 | P27487 | 6/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4483695 | 0.85 | P2RX7 (0.47) | CTSKDPP4DPP7KCNH2MAPK1 | |
| SCHEMBL4483683 | 0.85 | P2RX7 (0.47) | CTSKDPP4DPP7KCNH2MAPK1 | |
| SCHEMBL4483688 | 0.85 | P2RX7 (0.47) | CTSKDPP4DPP7KCNH2MAPK1 | |
| Trifluoroacetic Acid SCHEMBL4484957 | 0.73 | DPP4 (0.44) | DPP4DPP7KCNH2TSHRFAAH | |
| Trifluoroacetic Acid SCHEMBL4484950 | 0.73 | DPP4 (0.44) | DPP4DPP7KCNH2TSHRFAAH | |
| Hydrochloric Acid SCHEMBL4480328 | 0.71 | KMT2A (0.59) | DPP4DPP7TSHRFAAHCYP3A4 | |
| SCHEMBL29268591 | 0.71 | CTSK (0.60) | CTSKDPP4DPP7KCNH2TSHR | |
| SCHEMBL21522663 | 0.71 | CTSK (0.60) | CTSKDPP4DPP7KCNH2TSHR | |
| SCHEMBL29268593 | 0.71 | CTSK (0.60) | CTSKDPP4DPP7KCNH2TSHR | |
| SCHEMBL5943236 | 0.71 | PREP (0.44) | CTSKTSHRCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |