Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL4485013

C[n+]1c(F)ccc2ccccc21.O=S(=O)([O-])C(F)(F)F

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 10/20 0.40
ACHE P22303 7/20 0.40
GPR3 P46089 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL4881196 0.84 KDM4E (0.47) KCNH2ACHEGPR3KDM4EALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL4497025 0.83 KCNH2 (0.41) KCNH2ACHEGPR3KDM4EALDH1A1
Trifluoromethanesulfonic Acid SCHEMBL31472680 0.83 KCNH2 (0.41) KCNH2ACHEGPR3KDM4EALDH1A1
SCHEMBL4622504 0.83 ACHE (0.50) ACHE
Trifluoromethanesulfonic Acid SCHEMBL3855070 0.82 KCNH2 (0.43) KCNH2ACHEGPR3
Fluoride Ion SCHEMBL4495682 0.81 ACHE (0.49) ACHE
Trifluoromethanesulfonic Acid SCHEMBL6554225 0.81 ACHE (0.46) KCNH2ACHE
Trifluoromethanesulfonic Acid SCHEMBL11070399 0.81 KCNH2 (0.38) KCNH2ACHEGPR3
Trifluoromethanesulfonic Acid SCHEMBL5948989 0.78 KCNH2 (0.51) KCNH2ACHEGPR3
Trifluoromethanesulfonic Acid SCHEMBL7077338 0.78 GPR3 (0.41) KCNH2ACHEGPR3KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090234151-A1 Preparation of Mono-/Difluorinated Hydrocarbon Compounds RHODIA CHIMIE (FR) 2009-09-17 US claimed
US-20090234151-A1 Preparation of Mono-/Difluorinated Hydrocarbon Compounds RHODIA CHIMIE (FR) 2009-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090234151-A1 Preparation of Mono-/Difluorinated Hydrocarbon Compounds AHR, CYP2E1, CYP2F1 KCNH2 890/4885ACHE 3533/4885GPR3 541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.