Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 15/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL4495682 | 0.98 | ACHE (0.49) | ACHEPOLBKMT2ABCHEMEN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL4485013 | 0.83 | KCNH2 (0.40) | ACHE | |
| SCHEMBL1044982 | 0.74 | ACHE (0.47) | ACHEPOLBKMT2ABCHEMEN1 | |
| SCHEMBL30929898 | 0.74 | ACHE (0.47) | ACHEPOLBKMT2ABCHEMEN1 | |
| SCHEMBL10789148 | 0.73 | ACHE (0.46) | ACHEPOLBKMT2ABCHEMEN1 | |
| Hydrochloric Acid SCHEMBL6339464 | 0.73 | ACHE (0.46) | ACHEPOLBKMT2ABCHEMEN1 | |
| SCHEMBL21341559 | 0.73 | ACHE (0.46) | ACHEPOLBKMT2ABCHEMEN1 | |
| SCHEMBL13979479 | 0.73 | ACHE (0.46) | ACHEPOLBKMT2ABCHEMEN1 | |
| Iodide SCHEMBL2031115 | 0.73 | ACHE (0.50) | ACHEPOLBKMT2ABCHEMEN1 | |
| SCHEMBL4592722 | 0.73 | ACHE (0.49) | ACHEPOLBKMT2ABCHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904425-A1 | METHOD FOR PREPARING MONO- OR DIFLUORINATED HYDROCARBON COMPOUNDS | Rhodia Chimie SA (FR) | 2008-04-02 | — | — | EP | claimed |
| WO-2007010111-A1 | METHOD FOR PREPARING MONO- OR DIFLUORINATED HYDROCARBON COMPOUNDS | RHODIA CHIMIE (FR) | 2007-01-25 | — | — | WO | claimed |
| US-20090234151-A1 | Preparation of Mono-/Difluorinated Hydrocarbon Compounds | RHODIA CHIMIE (FR) | 2009-09-17 | — | — | US | disclosed |
| EP-1904425-A1 | METHOD FOR PREPARING MONO- OR DIFLUORINATED HYDROCARBON COMPOUNDS | Rhodia Chimie SA (FR) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007010111-A1 | METHOD FOR PREPARING MONO- OR DIFLUORINATED HYDROCARBON COMPOUNDS | RHODIA CHIMIE (FR) | 2007-01-25 | — | — | WO | disclosed |
| WO-2007010111-A1 | METHOD FOR PREPARING MONO- OR DIFLUORINATED HYDROCARBON COMPOUNDS | RHODIA CHIMIE (FR) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234151-A1 | Preparation of Mono-/Difluorinated Hydrocarbon Compounds | AHR, CYP2E1, CYP2F1 | ACHE 3533/4885POLB 137/4885KMT2A 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.