SCHEMBL448526

SCHEMBL448526

CCCOCCCC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.54
GPR84 Q9NQS5 7/20 0.52
PPARG P37231 7/20 0.52
PPARD Q03181 7/20 0.52
PPARA Q07869 7/20 0.52
HDAC11 Q96DB2 5/20 0.52
TSHR P16473 5/20 0.52
PTPN1 P18031 3/20 0.52
ALDH1A1 P00352 3/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
FABP4 P15090 2/20 0.52
KMT2A Q03164 2/20 0.52
SLC22A6 Q4U2R8 2/20 0.52
SLC22A8 Q8TCC7 1/20 0.52
MEN1 O00255 1/20 0.52
ESR1 P03372 1/20 0.52
ALOX15 P16050 1/20 0.52
PDE4A P27815 1/20 0.52
PDE3A Q14432 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9503728 0.98 AKR1B1 (0.52) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL31151079 0.98 AKR1B1 (0.52) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL10138469 0.98 AKR1B1 (0.52) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL448062 0.93 AKR1B1 (0.58) AKR1B1GPR84PPARGPPARDPPARA
Adipic Acid SCHEMBL12980712 0.93 AKR1B1 (0.64) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL850569 0.91 GPR84 (0.60) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL16401918 0.91 GPR84 (0.60) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL20725734 0.91 AKR1B1 (0.56) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL7198133 0.91 GPR84 (0.60) AKR1B1GPR84PPARGPPARDPPARA
SCHEMBL2721732 0.91 GPR84 (0.60) AKR1B1GPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3683243-B1 PROCESS OF MANUFACTURE OF CATALYST AND PROPYLENE POLYMER THAT USE THIS OR COPOLYMER FOR PROPYLENE POLYMERIZATION HANWHA TOTALENERGIES PETROCHEMICAL CO LTD (KR) 2024-01-24 EP claimed
CN-103857751-A Composition for preparing alignment layer, alignment layer prepared therefrom, and retardation film DONGWOO FINE CHEM CO LTD 2014-06-11 CN claimed
CN-100429248-C Manufacturing method of acrylic copolymer resin for layer insulation film for TFT-LCD DONGJIN SAEMIGUNG CO LTD (KR) 2008-10-29 CN claimed
CN-1693322-A Manufacturing method of acrylic copolymer resin for layer insulation film for TFT-LCD DONGJIN SAEMIGUNG CO LTD (KR) 2005-11-09 CN claimed
US-20250296915-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2025-09-25 US disclosed
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2023-08-17 US disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
CN-104808439-B Photoresist composition and method for manufacturing thin film transistor substrate 三星显示有限公司 2019-12-31 CN disclosed
US-10391750-B2 Cover window plate and image display device including the same DONGWOO FINE-CHEM CO., LTD. (KR) 2019-08-27 US disclosed
US-20180178494-A1 COVER WINDOW PLATE AND IMAGE DISPLAY DEVICE INCLUDING THE SAME DONGWOO FINE-CHEM CO., LTD. (KR) 2018-06-28 US disclosed
CN-104755510-B Ziegler natta catalyst system of internal donor and preparation method thereof is used as comprising 1,2 phenylene diester 印度石油有限公司 2017-11-07 CN disclosed
EP-0665015-A2 Combination treatment for osteoporosis ELI LILLY AND COMPANY (US) 1995-08-02 EP disclosed
EP-0657162-A1 Methods for lowering serum cholesterol ELI LILLY AND COMPANY (US) 1995-06-14 EP disclosed
EP-0651998-A1 Methods for inhibiting bone loss ELI LILLY AND COMPANY (US) 1995-05-10 EP disclosed
EP-0650724-A1 Methods for inhibiting uterine fibrosis ELI LILLY AND COMPANY (US) 1995-05-03 EP disclosed
US-5393763-A Administering benzothiophenes such as raloxifene hydrochloride ELI LILLY AND COMPANY (US) 1995-02-28 US disclosed
EP-0635264-A2 Antiestrogens as hypoglycemic agents ELI LILLY AND COMPANY (US) 1995-01-25 EP disclosed
EP-0605193-A1 Use of benzothiophenes for treatment of hypercholesterolaemia ELI LILLY AND COMPANY (US) 1994-07-06 EP disclosed
EP-0584952-A1 Improvements in or relating to benzothiophenes ELI LILLY AND COMPANY (US) 1994-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296915-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP AKR1B1 4357/4885GPR84 2049/4885PPARG 3873/4885
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP AKR1B1 4239/4885GPR84 2787/4885PPARG 4135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.