SCHEMBL4485265

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4476807	0.91	MEN1 (0.63)	CNR2BCHEACHEBACE1MEN1
	SCHEMBL28226193	0.89	CYP1A2 (0.66)	CNR2DRD2DRD1DRD4DRD5
	SCHEMBL20148958	0.85	ACHE (0.60)	BCHEACHEBACE1MEN1KMT2A
	SCHEMBL4691061	0.84	CNR2 (0.90)	CNR2DRD2DRD1DRD4DRD5
	SCHEMBL20645686	0.82	KDM4E (0.52)	MEN1KMT2APDE2A
	SCHEMBL24460749	0.82	CNR2 (0.70)	CNR2DRD2DRD1DRD4DRD5
	SCHEMBL22795508	0.81	CYP2D6 (0.62)	CNR2DRD2DRD1DRD4DRD5
	SCHEMBL22794988	0.81	CYP2D6 (0.62)	CNR2DRD2DRD1DRD4DRD5
	SCHEMBL14642000	0.81	MEN1 (0.61)	CNR2DRD2DRD1DRD4DRD5
	SCHEMBL22794990	0.81	CYP2D6 (0.62)	CNR2DRD2DRD1DRD4DRD5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.