SCHEMBL4485563

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4479824	0.85	NPSR1 (0.59)	NPSR1DRD3DRD2HTR2ALMNA
	SCHEMBL13630155	0.85	NPSR1 (0.59)	NPSR1DRD3DRD2HTR2ALMNA
	SCHEMBL13630154	0.85	NPSR1 (0.59)	NPSR1DRD3DRD2HTR2ALMNA
	SCHEMBL3865455	0.84	DRD2 (0.55)	DRD3DRD2HTR2ALMNAHTR1A
	SCHEMBL3863133	0.84	ALDH1A1 (0.52)	DRD3DRD2HTR2ALMNAHTR1A
	SCHEMBL3866840	0.83	DRD2 (0.56)	NPSR1DRD3DRD2HTR2ALMNA
	SCHEMBL4493085	0.82	DRD2 (0.49)	DRD3DRD2HTR2ALMNAHTR1A
	SCHEMBL4484259	0.82	DRD2 (0.52)	DRD3DRD2HTR2ALMNAHTR1A
	SCHEMBL17226569	0.81	NPSR1 (0.58)	NPSR1DRD3DRD2HTR2ALMNA
	SCHEMBL3845181	0.80	DRD2 (0.52)	DRD3DRD2HTR2ALMNAHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.