SCHEMBL4486140

SCHEMBL4486140

COc1c(O)ccc(CO)c1OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.40
KLF10 Q13118 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA1 P00915 2/20 0.38
CA12 O43570 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA13 Q8N1Q1 1/20 0.38
PDE4A P27815 1/20 0.38
PDE4B Q07343 1/20 0.38
PDE4C Q08493 1/20 0.38
PDE4D Q08499 1/20 0.38
PKM P14618 1/20 0.37
CA2 P00918 1/20 0.37
TRPV1 Q8NER1 1/20 0.37
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10748552 0.88 CA2 (0.39) MAPTKLF10TDP1CA1CA12
SCHEMBL17008599 0.85 KDM4E (0.39) MAPTKLF10TDP1CA1CA12
SCHEMBL11231888 0.84 TRPV1 (0.37) MAPTKLF10TDP1CA1CA12
SCHEMBL14539258 0.83 PDCD1 (0.39) MAPTKLF10TDP1CA1CA12
SCHEMBL5610344 0.83 PDCD1 (0.39) MAPTKLF10TDP1PDE4APDE4B
SCHEMBL12504376 0.83 TRPV1 (0.43) TDP1CA1CA12CA7CA9
SCHEMBL1836066 0.81 CA1 (0.48) MAPTCA1CA12CA7CA9
SCHEMBL22699664 0.81 TAAR1 (0.39) MAPTTDP1CA1CA12CA7
SCHEMBL69925 0.81 TDP1 (0.52) MAPTTDP1CA1CA12CA7
SCHEMBL29403778 0.81 TDP1 (0.52) MAPTTDP1CA1CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1915333-B1 PROCESS FOR THE PREPARATION OF UBIHYDROQUINONES AND UBIQUINONES DSM IP ASSETS BV (NL) 2015-06-03 EP disclosed
US-7601877-B2 Condensation of a prenol or isoprenol with a hydroquinone or derivative in the presence of 0.005-1.0 mol percent of a Bronsted or Lewis acid catalyst selected from a bismuth, indium or Group 3 chloride, a heteropolyacid, and an NH- or a CH-acidic compound, oxidizing the ubihydroquinone; improved kinetics DSM IP ASSETS B.V. (NL) 2009-10-13 US disclosed
US-20080275275-A1 Process for the Preparation of Ubihydroquinones and Ubiquinones DSM IPASSETS B.V. (NL) 2008-11-06 US disclosed
EP-1915333-A1 PROCESS FOR THE PREPARATION OF UBIHYDROQUINONES AND UBIQUINONES DSMIP Assets B.V. (NL) 2008-04-30 EP disclosed
WO-2007017168-A1 PROCESS FOR THE PREPARATION OF UBIHYDROQUINONES AND UBIQUINONES DSM IP ASSETS B.V. (NL) 2007-02-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080275275-A1 Process for the Preparation of Ubihydroquinones and Ubiquinones UBE2D3, UBE2L3, UBE2I MAPT 2939/4885KLF10 4303/4885TDP1 4456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.