Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14539258 | 0.84 | PDCD1 (0.39) | PDCD1CD274KDM4EALDH1A1MAPT | |
| SCHEMBL4486140 | 0.83 | MAPT (0.40) | KDM4EALDH1A1MAPTKLF10TDP1 | |
| SCHEMBL697386 | 0.80 | KMT2A (0.48) | PDCD1CD274KDM4EALDH1A1MAPT | |
| SCHEMBL68271 | 0.78 | TDP1 (0.44) | SCN5AKDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL17008599 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1MAPTKLF10TDP1 | |
| SCHEMBL16687419 | 0.77 | PDCD1 (0.37) | PDCD1CD274KDM4EALDH1A1MAPT | |
| SCHEMBL31285652 | 0.77 | MAPT (0.41) | PDCD1CD274KDM4EALDH1A1MAPT | |
| SCHEMBL3468895 | 0.76 | TYR (0.42) | PDCD1CD274KDM4EALDH1A1MAPT | |
| SCHEMBL10748552 | 0.76 | CA2 (0.39) | KDM4EALDH1A1MAPTKLF10TDP1 | |
| SCHEMBL15868589 | 0.76 | PDCD1 (0.36) | PDCD1CD274KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007095631-A2 | NEW DRUG DELIVERY SYSTEM FOR CROSSING THE BLOOD BRAIN BARRIER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-08-23 | — | — | WO | disclosed |