Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 4/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.36 |
| ▸ | PDE5A | O76074 | 3/20 | 0.36 |
| ▸ | PDE1A | P54750 | 3/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 3/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11231888 | 0.89 | TRPV1 (0.37) | CA2CA4MAPTKLF10CA1 | |
| SCHEMBL4486140 | 0.88 | MAPT (0.40) | CA2MAPTKLF10CA1CA12 | |
| SCHEMBL26046493 | 0.85 | HMGCR (0.43) | CA2CA4TRPV1POLB | |
| SCHEMBL22545546 | 0.83 | ALOX5 (0.44) | MAPTCYP3A4KDM4EALDH1A1GAA | |
| SCHEMBL17008599 | 0.82 | KDM4E (0.39) | CA2MAPTKLF10CA1CA12 | |
| SCHEMBL7948321 | 0.81 | BCL2 (0.41) | CYP3A4SMN1; SMN2POLB | |
| SCHEMBL26046416 | 0.81 | IAPP (0.45) | MAPTTRPV1PKMCYP3A4KDM4E | |
| SCHEMBL26046355 | 0.81 | POLB (0.55) | MAPTTDP1TRPV1KDM4EALDH1A1 | |
| SCHEMBL11238058 | 0.81 | KLF10 (0.38) | MAPTKLF10PKMKDM4EALDH1A1 | |
| SCHEMBL14539258 | 0.80 | PDCD1 (0.39) | CA2MAPTKLF10CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760773-B2 | Small molecule drug conjugates of gemcitabine monophosphate | MAVERIX ONCOLOGY, INC. (US) | 2023-09-19 | — | — | US | disclosed |
| CN-101678333-B | Process for preparing a hydroxyaromatic aldehyde | RHODIA OPERATIONS | 2014-01-01 | — | — | CN | disclosed |
| US-4683087-A | 2,2-ETHYLENE BIS(6-BROMOMETHYL-P-BENZOQUINONE | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1987-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11760773-B2 | Small molecule drug conjugates of gemcitabine monophosphate | ZYX, SLC7A5, GMPS | CA2 3394/4885CA4 1387/4885MAPT 4486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.