SCHEMBL4486933

SCHEMBL4486933

CCc1c(C(=O)O)c(C=O)n(C)c1CC1CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PLA2G1B P04054 9/20 0.43
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4505678 0.80 ALDH1A1 (0.33)
SCHEMBL4480830 0.78 ALDH1A1 (0.32)
SCHEMBL4491376 0.76 GAA (0.33)
SCHEMBL4499053 0.75 AGTR1 (0.36) PLA2G1B
SCHEMBL4497030 0.73
SCHEMBL4480912 0.71
SCHEMBL4491009 0.70 ALDH1A1 (0.43) L3MBTL1
SCHEMBL4493426 0.68
SCHEMBL4488837 0.65 ALDH1A1 (0.33) L3MBTL1
SCHEMBL4488870 0.65 MEN1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7504429-B2 Tyrosine kinase inhibitors MERCK & CO., INC. (US) 2009-03-17 US claimed