SCHEMBL448710

SCHEMBL448710

[O]CCC(F)(F)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL866586 0.80
SCHEMBL866920 0.80
SCHEMBL864383 0.78 CA1 (0.31)
SCHEMBL5505744 0.78 THRB (0.31)
SCHEMBL1358665 0.76
SCHEMBL1434180 0.76 LMNA (0.35)
SCHEMBL6889577 0.76 LMNA (0.35)
SCHEMBL6898875 0.76
SCHEMBL6873310 0.76 LMNA (0.35)
SCHEMBL6906530 0.76 LMNA (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240148699-A1 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-05-09 US disclosed
WO-2023174773-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2023-09-21 WO disclosed
EP-3303305-B9 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES FMC CORP (US) 2022-07-13 EP disclosed
US-11273168-B2 Methods of treating anxiety by administering a substituted quinolone OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2022-03-15 US disclosed
EP-3943486-A1 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES FMC Corporation (US) 2022-01-26 EP disclosed
EP-3303305-B1 2-(PHENYLOXY OR PHENYLTHIO)PYRIMIDINE DERIVATIVES AS HERBICIDES FMC CORP (US) 2022-01-05 EP disclosed
US-20210300879-A1 PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES FMC CORP (US) 2021-09-30 US disclosed
US-11053204-B2 Pyrimidinyloxy benzene derivatives as herbicides FMC CORPORATION (US) 2021-07-06 US disclosed
CN-104649916-B Photocrosslinkable materials 罗利克有限公司 2020-12-01 CN disclosed
US-20200281951-A1 HETEROCYCLIC COMPOUNDS FOR TREATING OR PREVENTING DISORDERS CAUSED BY REDUCED NEUROTRANSMISSION OF SEROTONIN, NOREPHNEPHRINE OR DOPAMINE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2020-09-10 US disclosed
WO-2004002943-A1 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2004-01-08 WO disclosed
EP-1310497-A1 PYRAZOLE DERIVATIVES, PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT AND PROCESS FOR THEIR PRODUCTION Nihon Nohyaku Co., Ltd. (JP) 2003-05-14 EP disclosed
US-6335357-B1 1-ARYL-3-CYANO-5-(HET)ARYLALKYLAMINOPYRAZOLE DERIVATIVES; INSECTICIDES FOR AGRICULTURE AND HORTICULTURE MITSUBISHI CHEMICAL CORPORATION (JP) 2002-01-01 US disclosed
EP-0976737-A1 PYRAZOLE DERIVATIVES, PROCESS FOR PREPARING THE SAME, INTERMEDIATES, AND PEST CONTROL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT MITSUBISHI CHEMICAL CORPORATION (JP) 2000-02-02 EP disclosed
EP-0891975-A1 PYRAZOLES AND AGRICULTURAL CHEMICALS CONTAINING THEM AS ACTIVE INGREDIENTS MITSUBISHI CHEMICAL CORPORATION (JP) 1999-01-20 EP disclosed
EP-0726266-B1 Indazole compounds and the use thereof as fungicides, insecticides and miticides MITSUBISHI CHEM CORP (JP) 1998-01-07 EP disclosed
US-5705453-A INSECTICIDES, MITICIDES, FUNGICIDES MITSUBISHI CHEMICAL CORPORATION (JP) 1998-01-06 US disclosed
EP-0726266-A1 Indazole compounds and the use thereof as fungicides, insecticides and miticides MITSUBISHI CHEMICAL CORPORATION (JP) 1996-08-14 EP disclosed
US-4968805-A Pyrazole derivatives and insecticidal fungicidal and miticidal compositions thereof MITSUBISHI KASEI CORPORATION (JP) 1990-11-06 US disclosed
EP-0329020-A1 Pyrazole derivatives, processes for their manufacture and insecticidal, miticidal and fungicidal compositions containg the derivatives as active ingredients MITSUBISHI KASEI CORPORATION (JP) 1989-08-23 EP disclosed