SCHEMBL5505744

SCHEMBL5505744

[O]CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6906530 0.97 LMNA (0.35) THRBLMNA
SCHEMBL1434180 0.97 LMNA (0.35) THRBLMNA
SCHEMBL1984822 0.97 LMNA (0.35) THRBLMNA
SCHEMBL6873310 0.97 LMNA (0.35) THRBLMNA
SCHEMBL6889577 0.97 LMNA (0.35) THRBLMNA
SCHEMBL866920 0.91
SCHEMBL28445967 0.83
SCHEMBL28444858 0.81 THRB (0.32) THRBLMNA
SCHEMBL28438612 0.81 THRB (0.32) THRBLMNA
SCHEMBL3058414 0.81 LMNA (0.37) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478400-A Polyimide and diamine monomer containing tetrabiphenyl derivative structure and preparation method thereof 中山大学 2023-07-25 CN claimed
CN-116478400-A Polyimide and diamine monomer containing tetrabiphenyl derivative structure and preparation method thereof 中山大学 2023-07-25 CN disclosed
WO-2021153720-A1 3-ALKOXY BENZOIC ACID AMIDE DERIVATIVE, AND PEST CONTROL AGENT クミアイ化学工業株式会社 2021-08-05 WO disclosed
CN-111566524-A Optical laminate and display device 住友化学株式会社 2020-08-21 CN disclosed
US-7157442-B2 Antibacterial compound SANKYO COMPANY, LIMITED (JP) 2007-01-02 US disclosed
EP-1209166-B1 NOVEL A-500359 DERIVATIVES SANKYO CO (JP) 2004-03-31 EP disclosed
US-20030171330-A1 Antibacterial compound SANKYO COMPANY, LIMITED (JP) 2003-09-11 US disclosed
EP-1209166-A1 NOVEL A-500359 DERIVATIVES Sankyo Company, Limited (JP) 2002-05-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030171330-A1 Antibacterial compound TLR1, MPO, O60361 THRB 3349/4885LMNA 4477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.