SCHEMBL4487160

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4487073	0.94	KDM4E (0.53)	HPGDSKDM4EASPHKDM8RIOX2
	SCHEMBL4477510	0.91	KDM4E (0.47)	HPGDSKDM4EASPHKDM8RIOX2
	SCHEMBL4489260	0.91	HPGDS (0.55)	HPGDSKDM4EASPHKDM8RIOX2
	SCHEMBL4490500	0.90	CTNNB1 (0.51)	HPGDSKDM4EASPHKDM8RIOX2
	SCHEMBL4482149	0.90	KDM4E (0.47)	HPGDSKDM4EASPHKDM8RIOX2
	SCHEMBL4484614	0.89	KDM4E (0.46)	HPGDSKDM4EASPHKDM8RIOX2
	SCHEMBL4492223	0.88	CCR9 (0.47)	HPGDSKDM4EASPHKDM8RIOX2
	SCHEMBL4500058	0.86	SMN1; SMN2 (0.53)	HPGDSTSHRMAPTSMN1; SMN2ALDH1A1
	SCHEMBL4491139	0.86	CA1 (0.52)	ALDH1A1CA1CA2HPGD
	SCHEMBL4489494	0.85	HIF1A (0.60)	HPGDSKDM4ETSHRCTNNB1TCF7L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.