SCHEMBL4489260

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4487073	0.94	KDM4E (0.53)	HPGDSEGFRNPC1RAB9ATP53
	SCHEMBL4500058	0.93	SMN1; SMN2 (0.53)	HPGDSEGFRRAB9ASMN1; SMN2ALDH1A1
	SCHEMBL4487160	0.91	HPGDS (0.47)	HPGDSEGFRNPC1RAB9ASMN1; SMN2
	SCHEMBL4477510	0.91	KDM4E (0.47)	HPGDSEGFRSMN1; SMN2TP53ALDH1A1
	SCHEMBL4490500	0.90	CTNNB1 (0.51)	HPGDSLMNAKDM4EMAPTASPH
	SCHEMBL4482149	0.90	KDM4E (0.47)	HPGDSEGFRNPC1RAB9AKDM4E
	SCHEMBL4489494	0.90	HIF1A (0.60)	HPGDSNPC1RAB9ASMN1; SMN2TP53
	SCHEMBL4496183	0.89	LMNA (0.46)	HPGDSEGFRNPC1RAB9ASMN1; SMN2
	SCHEMBL4484547	0.89	APP (0.48)	HPGDSEGFRNPC1RAB9ASMN1; SMN2
	SCHEMBL4501469	0.89	APEX1 (0.49)	HPGDSEGFRSMN1; SMN2LMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.