SCHEMBL4487791

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4490345	0.84	FABP3 (0.51)	KDM4EMAPTALDH1A1CLK1HPGD
	SCHEMBL5207273	0.84	AKR1C3 (0.46)	KDM4EMAPTALDH1A1CLK1HPGD
	SCHEMBL4478341	0.83	CDC25B (0.52)	KDM4EMAPTGAAALDH1A1HPGD
	SCHEMBL4484788	0.83	AKR1C3 (0.46)	KDM4EMAPTALDH1A1L3MBTL1HPGD
	SCHEMBL4482947	0.82	AKR1C3 (0.58)	KDM4EMAPTGAAALDH1A1HPGD
	SCHEMBL4491211	0.82	ALDH1A1 (0.47)	KDM4EMAPTGAAALDH1A1HPGD
	SCHEMBL5204839	0.81	KDM4E (0.52)	KDM4EMAPTGAAALDH1A1CLK1
	SCHEMBL5203654	0.80	KDM4E (0.60)	KDM4EMAPTGAAALDH1A1CLK1
	SCHEMBL4495216	0.79	CXCR5 (0.46)	KDM4EMAPTGAAL3MBTL1MEN1
	SCHEMBL5208739	0.78	KMT2A (0.53)	MAPTALDH1A1HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.