SCHEMBL4495216

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4478341	0.81	CDC25B (0.52)	MEN1KMT2AKDM4EMAPTGAA
	SCHEMBL5207273	0.80	AKR1C3 (0.46)	MEN1KMT2AKDM4EMAPTAKR1C3
	SCHEMBL4490345	0.80	FABP3 (0.51)	MEN1KMT2AKDM4EMAPTAKR1C3
	SCHEMBL4487791	0.79	KDM4E (0.53)	MEN1KMT2AKDM4EMAPTGAA
	SCHEMBL4484788	0.79	AKR1C3 (0.46)	KDM4EMAPTAKR1C3AKR1C2POLB
	SCHEMBL5208739	0.78	KMT2A (0.53)	MEN1KMT2AMAPTLMNASMN1; SMN2
	SCHEMBL4491211	0.78	ALDH1A1 (0.47)	MEN1KMT2AKDM4EMAPTGAA
	SCHEMBL4482947	0.78	AKR1C3 (0.58)	MEN1KMT2AKDM4EMAPTGAA
	SCHEMBL5207474	0.78	RECQL (0.50)	MEN1KMT2AKDM4EMAPTP2RX7
	SCHEMBL5202876	0.75	AKR1C3 (0.62)	MEN1KMT2AKDM4EMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.