Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4491379 | 0.87 | FBP1 (0.34) | ALDH1A1POLBKMT2A | |
| SCHEMBL4502842 | 0.80 | ALDH1A1 (0.36) | ALDH1A1POLBKMT2A | |
| SCHEMBL4497032 | 0.78 | ALDH1A1 (0.31) | ALDH1A1POLBKMT2A | |
| SCHEMBL4480914 | 0.75 | LDHA (0.33) | ALDH1A1POLBKMT2A | |
| SCHEMBL4463781 | 0.67 | LDHA (0.33) | ALDH1A1POLBKMT2A | |
| SCHEMBL4491011 | 0.67 | SMN1; SMN2 (0.44) | ALDH1A1KMT2A | |
| SCHEMBL4494939 | 0.65 | — | — | |
| SCHEMBL4505401 | 0.65 | ALDH1A1 (0.30) | ALDH1A1POLBKMT2A | |
| SCHEMBL4497398 | 0.65 | ALDH1A1 (0.33) | ALDH1A1POLBKMT2A | |
| SCHEMBL4497337 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |