Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8791016 | 0.83 | ALDH1A1 (0.52) | MAPK1ALDH1A1KDM4EPOLBPKM | |
| SCHEMBL16452770 | 0.77 | TDP1 (0.45) | MAPK1ALDH1A1KDM4EPOLBPKM | |
| SCHEMBL4498133 | 0.77 | ALDH1A1 (0.57) | MAPK1ALDH1A1KDM4EPOLBPKM | |
| SCHEMBL8947294 | 0.75 | MAPK1 (0.61) | MAPK1ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL8947156 | 0.74 | MAPK1 (0.60) | MAPK1ALDH1A1KDM4EPKMGAA | |
| SCHEMBL15475206 | 0.72 | MAPK1 (0.55) | MAPK1ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL15243006 | 0.72 | GAA (0.41) | MAPK1ALDH1A1KDM4EPOLBPKM | |
| SCHEMBL20518663 | 0.72 | MAPK1 (1.00) | MAPK1ALDH1A1KDM4EPOLBPKM | |
| SCHEMBL8791215 | 0.71 | KMT2A (0.41) | MAPK1ALDH1A1KDM4EPOLBPKM | |
| SCHEMBL8843434 | 0.71 | HTT (0.57) | MAPK1ALDH1A1KDM4EGAACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572753-B2 | Tetrazole fungicides | CHEMTURA CORPORATION (US) | 2009-08-11 | — | — | US | disclosed |
| US-20070060631-A1 | 2-cyanomethyl-5-(3-substituted phenyl or 5-substituted thien-2-yl)-2H-tetrazoles; agricultural fungicides such as for rice blast | CROMPTON COLORS INCORPORATED | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060631-A1 | 2-cyanomethyl-5-(3-substituted phenyl or 5-substituted thien-2-yl)-2H-tetrazoles; agricultural fungicides such as for rice blast | TH, HAO2, TDO2 | MAPK1 2373/4885ALDH1A1 2475/4885KDM4E 740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.