Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | HNF4A | P41235 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | MMP15 | P51511 | 1/20 | 0.32 |
| ▸ | MMP16 | P51512 | 1/20 | 0.32 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4495537 | 0.83 | ERN1 (0.39) | FFAR1GRM5 | |
| SCHEMBL4482502 | 0.81 | FLT4 (0.30) | RAB9AALDH1A1 | |
| SCHEMBL4490395 | 0.77 | — | — | |
| SCHEMBL4505401 | 0.75 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL4494939 | 0.75 | — | — | |
| SCHEMBL4491011 | 0.75 | SMN1; SMN2 (0.44) | RAB9ANPC1ALDH1A1LDHALDHB | |
| SCHEMBL4497337 | 0.74 | — | — | |
| SCHEMBL4486266 | 0.73 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1 | |
| SCHEMBL4489148 | 0.70 | ALDH1A1 (0.46) | RAB9ANPC1ALDH1A1NPSR1TDP1 | |
| SCHEMBL4480914 | 0.69 | LDHA (0.33) | ALDH1A1LDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504429-B2 | Tyrosine kinase inhibitors | MERCK & CO., INC. (US) | 2009-03-17 | — | — | US | claimed |