Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL555172 | 0.90 | EPHX2 (0.45) | EPHX2TET2RECQLTSHRMETAP1 | |
| SCHEMBL8851131 | 0.89 | EPHX2 (0.42) | EPHX2TET2RECQLTSHRMETAP1 | |
| SCHEMBL9031402 | 0.83 | HRH3 (0.34) | EPHX2GAA | |
| SCHEMBL9031766 | 0.81 | METAP1 (0.33) | METAP1 | |
| SCHEMBL4450020 | 0.78 | — | — | |
| SCHEMBL4488482 | 0.77 | METAP1 (0.41) | METAP1 | |
| Hydrochloric Acid SCHEMBL76321 | 0.77 | EPHX2 (0.47) | EPHX2TET2RECQLTSHRMETAP1 | |
| SCHEMBL555793 | 0.76 | KDM4E (0.40) | EPHX2TSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL1977433 | 0.75 | EPHX2 (0.59) | EPHX2KDM4EKMT2A | |
| SCHEMBL7440501 | 0.75 | EPHX2 (0.55) | EPHX2TET2RECQLTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7485647-B2 | 2-aminoquinoline derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-02-03 | — | — | US | claimed |