SCHEMBL448934

SCHEMBL448934

O=S(=O)(O)c1ccc2cc(O)c(S(=O)(=O)O)cc2c1.[NaH]

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NT5E P21589 3/20 0.50
HSD17B10 Q99714 5/20 0.49
ALDH1A1 P00352 4/20 0.49
CASP6 P55212 3/20 0.49
CYP2C9 P11712 3/20 0.49
CYP2C19 P33261 2/20 0.49
NSD2 O96028 3/20 0.46
SNCA P37840 2/20 0.46
PTPN11 Q06124 3/20 0.43
DUSP3 P51452 2/20 0.43
PTPN5 P54829 2/20 0.43
CASP7 P55210 1/20 0.43
CYP1A2 P05177 3/20 0.43
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
MEN1 O00255 1/20 0.42
THRB P10828 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
PRMT1 Q99873 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27722383 1.00 NT5E (0.50) NT5EHSD17B10ALDH1A1CASP6CYP2C9
SCHEMBL1432844 1.00 NT5E (0.50) NT5EHSD17B10ALDH1A1CASP6CYP2C9
SCHEMBL27701841 1.00 NT5E (0.50) NT5EHSD17B10ALDH1A1CASP6CYP2C9
SCHEMBL29364767 0.98 NT5E (0.51) NT5EHSD17B10ALDH1A1CASP6CYP2C9
SCHEMBL2926553 0.98 NT5E (0.51) NT5EHSD17B10ALDH1A1CASP6CYP2C9
SCHEMBL589951 0.98 NT5E (0.51) NT5EHSD17B10ALDH1A1CASP6CYP2C9
SCHEMBL31615002 0.98 NT5E (0.51) NT5EHSD17B10ALDH1A1CASP6CYP2C9
SCHEMBL30607134 0.98 NT5E (0.51) NT5EHSD17B10ALDH1A1CASP6CYP2C9
Potassium SCHEMBL18274866 0.96 NT5E (0.50) NT5EHSD17B10ALDH1A1CASP6CYP2C9
SCHEMBL18274864 0.96 NT5E (0.50) NT5EHSD17B10ALDH1A1CASP6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11752086-B2 Topical formulations and methods MYOCEPT INC. (US) 2023-09-12 US disclosed
CN-111182884-B Inorganic sunscreen coated with adducts of hydroxycinnamic esters and silanols 维佐尔有限责任公司 2023-01-31 CN disclosed
CN-113698792-B Preparation method of azo lake organic pigment capable of reducing aromatic amine residues 百合花集团股份有限公司 2022-05-10 CN disclosed
CN-110462108-B Electroplating solution 三菱综合材料株式会社 2022-02-01 CN disclosed
CN-113698792-A Preparation method of azo lake organic pigment capable of reducing aromatic amine residues 百合花集团股份有限公司 2021-11-26 CN disclosed
US-20210179975-A1 COMPOSITION CONTAINING LANTHANIDE METAL COMPLEX SPECIALTY OPERATIONS FRANCE (FR) 2021-06-17 US disclosed
CN-108409542-B Method for synthesizing 2, 3-dihydroxynaphthalene 南通柏盛化工有限公司 2020-12-01 CN disclosed
CN-108530465-B Visible light sensitive information recording material and preparation method thereof 北京化工大学 2020-06-05 CN disclosed
CN-110612093-A Topical formulations and methods 麦欧赛普特股份有限公司 2019-12-24 CN disclosed
US-20170105968-A1 Compositions and Methods for Treatment of Inflammatory Skin Conditions Using Allantoin SCIODERM, INC. (US) 2017-04-20 US disclosed
US-20020054895-A1 And at least one anionic or nonionic emulsifier that is substantially hydrophilic and is soluble in water; skin protectants ALWYN COMPANY, INC. 2002-05-09 US disclosed
US-20020055531-A1 Methods for treatment of inflammatory diseases SWEEN, MAURICE ALWYN 2002-05-09 US disclosed
US-6376557-B1 TRANSDERMAL SUPPLYING ZAVERI CHANDA BHUWALKA (US) 2002-04-23 US disclosed
WO-2001068107-A1 HAIR RESTORATION FORMULATION ZAVERI CHANDA BHUWALKA (US) 2001-09-20 WO disclosed
US-5642209-A FOR EXPOSING A PHOTOSENSITIVE SUBSTRATE BAKER KENNETH M (US) 1997-06-24 US disclosed
US-5427677-A Using a naphthalenesulfonic acid LEARONAL, INC. (US) 1995-06-27 US disclosed
EP-0613028-A2 Directional light filter and holographic projector system for its production Baker, Kenneth M. (US) 1994-08-31 EP disclosed
US-5286704-A Heat-sensitive recording medium HONSHU PAPER CO., LTD. (JP) 1994-02-15 US disclosed
EP-0496017-A1 Heat-sensitive recording medium HONSHU PAPER CO., LTD. (JP) 1992-07-29 EP disclosed
US-4659643-A A PHENOXY COMPOUND KANZAKI PAPER MANUFACTURING CO. LTD. (JP) 1987-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170105968-A1 Compositions and Methods for Treatment of Inflammatory Skin Conditions Using Allantoin CUTA, ITCH, ARG1 NT5E 4831/4885HSD17B10 3316/4885ALDH1A1 2205/4885
US-11752086-B2 Topical formulations and methods KRT18, ANXA3, VIP NT5E 2813/4885HSD17B10 2793/4885ALDH1A1 4831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.