SCHEMBL448975

SCHEMBL448975

CC(C)(C)c1ccc([I+](OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 13/20 0.37
CA1 P00915 12/20 0.37
CA9 Q16790 1/20 0.34
ALDH1A1 P00352 2/20 0.33
RORA P35398 1/20 0.33
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
PDK1 Q15118 1/20 0.31
PDK2 Q15119 1/20 0.31
PDK3 Q15120 1/20 0.31
PDK4 Q16654 1/20 0.31
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31
FFAR1 O14842 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3090902 1.00 CA2 (0.37) CA2CA1CA9ALDH1A1RORA
SCHEMBL114860 0.99 CA1 (0.36) CA2CA1CA9ALDH1A1RORA
SCHEMBL3828157 0.94 CA1 (0.38) CA2CA1CA9ALDH1A1RORA
SCHEMBL548236 0.88 CA2 (0.39) CA2CA1CA9MMP1MMP2
SCHEMBL548592 0.87 CA1 (0.38) CA2CA1CA9
SCHEMBL5405594 0.87 CA1 (0.37) CA2CA1LMNA
SCHEMBL2897585 0.85 CA2 (0.39) CA2CA1CA9GAAF2
SCHEMBL4410699 0.85 NPC1 (0.36) CA2CA1LMNA
SCHEMBL2895496 0.84 CA2 (0.38) CA2CA1CA9ALDH1A1GAA
SCHEMBL3284975 0.84 CA2 (0.40) CA2CA1F2PRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 770 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10662274-B2 Self-immolative polymers, articles thereof, and methods of making and using same GEORGIA TECH RESEARCH CORPORATION (US) 2020-05-26 US claimed
US-20180155483-A1 SELF-IMMOLATIVE POLYMERS, ARTICLES THEREOF, AND METHODS OF MAKING AND USING SAME GEORGIA TECH RESEARCH CORPORATION 2018-06-07 US claimed
US-9740096-B2 Positive-tone, chemically amplified, aqueous-developable, permanent dielectric GEORGIA TECH RESEARCH CORPORATION (US) 2017-08-22 US claimed
US-20150160551-A1 POSITIVE-TONE, CHEMICALLY AMPLIFIED, AQUEOUS-DEVELOPABLE, PERMANENT DIELECTRIC GEORGIA TECH RESEARCH CORPORATION (US) 2015-06-11 US claimed
US-6821718-B2 EXHIBIT HIGH RESISTANCE TO REACTIVE ION ETCHING IN EMPLOYING OXYGEN AND/OR CHLORINE INTERNATIONAL BUSINESS MACHINES CORPORATION 2004-11-23 US claimed
US-6653045-B2 Negative resist containing a polysilsesquioxane polymer with pendant fused rings and sites for reaction with a crosslinking agent, an acid-sensitive glycolurils ascrosslinking agent, and a radiation sensitive generator INTERNATIONAL BUSINESS MACHINES CORPORATION 2003-11-25 US claimed
US-6344305-B1 AMPLIFIED SILICON-CONTAINING NEGATIVE-TONE RESIST COMPOSITION OF AQUEOUS BASE SOLUBLE SILICON-CONTAINING POLYMER HAVING PHENOLIC GROUP FOR O-ALKYLATION; ACID CATALYZABLE CROSSLINKING AGENT; ACID GENERATOR; SOLVENT; PHOTOSENSITIZER INTERNATIONAL BUSINESS MACHINES CORPORATION 2002-02-05 US claimed
US-12631962-B2 Resist composition and method for forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2026-05-19 US disclosed
US-12624392-B2 Molecular array generation using photoresist 10X GENOMICS, INC. (US) 2026-05-12 US disclosed
US-20250362597-A1 RESIST COMPOSITION AND RESIST FILM FORMING METHOD USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-11-27 US disclosed
US-20250321485-A1 RESIST AUXILIARY FILM COMPOSITION, AND PATTERN FORMING METHOD USING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-10-16 US disclosed
US-12393115-B2 Positive working photosensitive material MERCK PATENT GMBH (DE) 2025-08-19 US disclosed
WO-2025128332-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-06-19 WO disclosed
US-6200728-B1 Photoresist compositions comprising blends of photoacid generators SHIPLEY COMPANY, L.L.C. 2001-03-13 US disclosed
EP-1030221-A1 Photoresist compositions comprising blends of photoacid generators Shipley Company LLC (US) 2000-08-23 EP disclosed
US-6048672-A RELIEF IMAGES ON SUBSTRATES WITH TITANIUM NITRIDE SURFACES, HEATING, COATING, EXPOSURE AND DEVELOPMENT SHIPLEY COMPANY, L.L.C. (US) 2000-04-11 US disclosed
EP-0987600-A1 Antireflective coating compositions Shipley Company LLC (US) 2000-03-22 EP disclosed
US-6037107-A EXPOSING TO ACTIVATION RADIATION A POSITIVE WORKING PHOTORESIST COMPRISING AN ALKALI SOLUBLE RESIN SUBSTITUTED WITH AN ACID LABILE BLOCKING GROUP TO GENERATE HALOGENATED SULFONIC ACID BY PHOTOLYSIS SHIPLEY COMPANY, L.L.C. (US) 2000-03-14 US disclosed
EP-0939339-A1 Irradiation sensitive positive-tone resists using polymers containing two acid sensitive protecting groups International Business Machines Corporation (US) 1999-09-01 EP disclosed
EP-0938029-A2 Methods using photoresist compositions and articles produced therewith Shipley Company LLC (US) 1999-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12631962-B2 Resist composition and method for forming resist pattern TERB1, TERF2, LSM8 CA2 677/4885CA1 577/4885CA9 549/4885
US-12624392-B2 Molecular array generation using photoresist POLL, LIG4, LIG3 CA2 2965/4885CA1 3957/4885CA9 2236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.