SCHEMBL449149

SCHEMBL449149

CO[Si](C)(OC)N(C)C(=O)N(C)C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL451522 0.79 ALDH1A1 (0.32) ALDH1A1
SCHEMBL462267 0.79 KDM6B (0.30)
SCHEMBL4350855 0.77 ALDH1A1 (0.30) ALDH1A1
SCHEMBL3316208 0.75 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL9810877 0.75 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL11099925 0.70
SCHEMBL9846330 0.68 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL6523333 0.65 ALDH1A1 (0.50) ALDH1A1TSHR
SCHEMBL24760 0.65
SCHEMBL10944574 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP claimed
EP-3074450-B1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MAT INC (US) 2020-11-11 EP claimed
US-10174169-B2 Moisture curable compound with metal-arene complexes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-01-08 US claimed
US-9976028-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2018-05-22 US claimed
US-9944770-B2 Moisture curable compound with thiourea MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-04-17 US claimed
US-9914809-B2 Moisture curable composition with amino acids MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-13 US claimed
EP-2614107-B1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2018-02-21 EP claimed
US-20170260335-A1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MATERIALS INC. 2017-09-14 US claimed
US-20170174840-A1 MOISTURE CURABLE SILICONE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2017-06-22 US claimed
US-9663621-B2 Moisture curable compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-05-30 US claimed
EP-2797692-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION Momentive Performance Materials Inc. (US) 2014-11-05 EP claimed
US-20140316059-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS INC. 2014-10-23 US claimed
WO-2013165552-A2 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC (US) 2013-11-07 WO claimed
WO-2013158236-A2 MOSITURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-10-24 WO claimed
EP-2614107-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION Momentive Performance Materials Inc. (US) 2013-07-17 EP claimed
WO-2013101755-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-07-04 WO claimed
WO-2013101751-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-07-04 WO claimed
WO-2013070227-A1 MOISTURE CURABLE COMPOSITION OF A POLYMER HAVING SILYL GROUPS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-05-16 WO claimed
US-20120065308-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2012-03-15 US claimed
WO-2012033886-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-15 WO claimed