SCHEMBL451522

SCHEMBL451522

CO[Si](C)(OC)N(C)C(C)=O

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL449149 0.79 ALDH1A1 (0.30) ALDH1A1
SCHEMBL452932 0.79 ALDH1A1 (0.32) ALDH1A1
SCHEMBL462267 0.79 KDM6B (0.30)
SCHEMBL4350855 0.77 ALDH1A1 (0.30) ALDH1A1
SCHEMBL450855 0.76 ALDH1A1 (0.33) ALDH1A1
SCHEMBL10509860 0.73 ALDH1A1 (0.33) ALDH1A1
SCHEMBL202677 0.71 LMNA (0.31) ALDH1A1
SCHEMBL537585 0.71
SCHEMBL449837 0.71 CHRM1 (0.35) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL508215 0.70 LMNA (0.36) ALDH1A1CHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117801281-A Preparation method of alkoxy end-capped polysiloxane 浙江衢州硅宝化工有限公司 2024-04-02 CN claimed
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP claimed
EP-3074450-B1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MAT INC (US) 2020-11-11 EP claimed
US-10174169-B2 Moisture curable compound with metal-arene complexes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-01-08 US claimed
US-9976028-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2018-05-22 US claimed
US-9944770-B2 Moisture curable compound with thiourea MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-04-17 US claimed
US-9914809-B2 Moisture curable composition with amino acids MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-13 US claimed
EP-2614107-B1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2018-02-21 EP claimed
US-20170260335-A1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MATERIALS INC. 2017-09-14 US claimed
US-20170174840-A1 MOISTURE CURABLE SILICONE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2017-06-22 US claimed
EP-0137883-B1 END-CAPPING CATALYST FOR FORMING ALCOXY-FUNCTIONAL ONE COMPONENT RTV COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 1989-02-15 EP claimed
EP-0069256-B1 ONE PACKAGE, STABLE, MOISTURE CURABLE, POLYALKOXY-TERMINATED ORGANOPOLYSILOXANE COMPOSITIONS AND METHOD FOR MAKING GENERAL ELECTRIC COMPANY (US) 1988-09-07 EP claimed
US-4539367-A ROOM TEMPERATURE VULCANIZABLE SILICONE RUBBERS GENERAL ELECTRIC COMPANY (US) 1985-09-03 US claimed
US-4517352-A STABILIZING SILANE SCAVENGER, CONDENSATION CATALYST; SEALANTS, CAULKING GENERAL ELECTRIC COMPANY (US) 1985-05-14 US claimed
US-4515932-A ROOM TEMPERATURE VULCANIZATION GENERAL ELECTRIC COMPANY (US) 1985-05-07 US claimed
EP-0137883-A1 End-capping catalyst for forming alcoxy-functional one component RTV compositions GENERAL ELECTRIC COMPANY (US) 1985-04-24 EP claimed
US-4513115-A ROOM TEMPERATURE VULCANIZABLE POLYALKOXY-TERMINATED POLYSILOXANE AND HYDROLIZABLE SCAVENGER, SHELF LIFE GENERAL ELECTRIC COMPANY (US) 1985-04-23 US claimed
US-4395526-A SILANE SCAVENGER GENERAL ELECTRIC COMPANY (US) 1983-07-26 US claimed
WO-1983000156-A1 ONE PACKAGE, STABLE, MOISTURE CURABLE, POLYALKOXY-TERMINATED ORGANOPOLYSILOXANE COMPOSITIONS AND METHOD FOR MAKING GEN ELECTRIC (US) 1983-01-20 WO claimed
EP-0069256-A2 One package, stable, moisture curable, polyalkoxy-terminated organopolysiloxane compositions and method for making GENERAL ELECTRIC COMPANY (US) 1983-01-12 EP claimed