Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3316208 | 0.81 | ALDH1A1 (0.35) | ALDH1A1TSHRNFKB1THPOHSD17B10 | |
| SCHEMBL449149 | 0.75 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| SCHEMBL6523333 | 0.71 | ALDH1A1 (0.50) | ALDH1A1TSHRNFKB1THPOHSD17B10 | |
| SCHEMBL24760 | 0.71 | — | — | |
| SCHEMBL202677 | 0.71 | LMNA (0.31) | ALDH1A1TSHR | |
| Bromide SCHEMBL29640683 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL11149001 | 0.68 | — | — | |
| Water SCHEMBL28721441 | 0.68 | — | — | |
| Fluoride SCHEMBL28328959 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL31267456 | 0.68 | ALDH1A1 (0.47) | ALDH1A1TSHRNFKB1THPOHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041514-A | Polymeric reaction products of biphenols and organosilicon materials and method for making | GENERAL ELECTRIC COMPANY (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0398049-A2 | Polymeric reaction products of biphenols and organosilicon materials and method for making | GENERAL ELECTRIC COMPANY (US) | 1990-11-22 | — | — | EP | disclosed |
| US-4208492-A | ENGINEERING THERMOPLASTIC ELASTOMERS | UNION CARBIDE CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |
| US-4145504-A | High temperature carborane-siloxane elastomers intermediate polymeric products and process for preparation | UNION CARBIDE CORPORATION (US) | 1979-03-20 | — | — | US | disclosed |