Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585379 | 0.83 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1PKMKDM4ERAB9A | |
| SCHEMBL7797891 | 0.83 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1PKMKDM4ERAB9A | |
| SCHEMBL20381801 | 0.83 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1PKMKDM4ERAB9A | |
| SCHEMBL16592116 | 0.80 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1PKMKDM4ERAB9A | |
| SCHEMBL7023026 | 0.80 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1PKMKDM4ERAB9A | |
| SCHEMBL14234544 | 0.79 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1PKMKDM4ERAB9A | |
| SCHEMBL14350432 | 0.79 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1PKMKDM4ERAB9A | |
| SCHEMBL417669 | 0.79 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1PKMKDM4ERAB9A | |
| SCHEMBL14234396 | 0.78 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1PKMKDM4ERAB9A | |
| SCHEMBL4032772 | 0.77 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1PKMKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585883-B2 | Substituted pyridines and their uses | RIGEL PHARMACEUTICALS, INC. (US) | 2009-09-08 | — | — | US | disclosed |
| EP-1817303-A2 | SUBSTITUTED PYRIDINES WITH ACTIVITY ON SYK KINASE | Rigel Pharmaceuticals, Inc. (US) | 2007-08-15 | — | — | EP | disclosed |
| US-20060178407-A1 | Substituted pyridines and their uses | RIGEL PHARMACEUTICAL, INC. (US) | 2006-08-10 | — | — | US | disclosed |
| WO-2006050480-A2 | SUBSTITUTED PYRIDINES WITH ACTIVITY ON SYK KINASE | RIGEL PHARMACEUTICALS, INC. (US) | 2006-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178407-A1 | Substituted pyridines and their uses | KIT, CPA3, CMA1 | ALDH1A1 613/4885L3MBTL1 4496/4885PKM 2002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.