SCHEMBL449241

SCHEMBL449241

C=Cc1cc(C(C)C)ccc1C(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.40
LMNA P02545 2/20 0.38
TRPA1 O75762 2/20 0.36
PTGS1 P23219 1/20 0.36
CACNA1C Q13936 1/20 0.36
ACHE P22303 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
ALOX12 P18054 1/20 0.35
HTT P42858 1/20 0.35
HIF1A Q16665 1/20 0.35
NPC1 O15118 1/20 0.33
SCN4A P35499 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RNASEH1 O60930 1/20 0.33
PTPN1 P18031 1/20 0.33
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
CHRM1 P11229 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29366381 0.83 TYR (0.44) TYRLMNATRPA1PTGS1CACNA1C
SCHEMBL93686 0.83 TYR (0.44) TYRLMNATRPA1PTGS1CACNA1C
SCHEMBL30322428 0.79 LMNA (0.52) TYRLMNATRPA1PTGS1CACNA1C
SCHEMBL7122025 0.79 LMNA (0.52) TYRLMNATRPA1PTGS1CACNA1C
SCHEMBL7804607 0.79 LMNA (0.50) LMNATRPA1HTTCHRM1SLC6A2
SCHEMBL32671492 0.79 LMNA (0.50) LMNATRPA1HTTCHRM1SLC6A2
SCHEMBL605235 0.79 TYR (0.58) TYRLMNATRPA1PTGS1CACNA1C
SCHEMBL24173430 0.78 ALDH1A1 (0.43) TYRLMNATRPA1PTGS1CACNA1C
SCHEMBL22422813 0.78 ALDH1A1 (0.47) TYRLMNATRPA1PTGS1CACNA1C
SCHEMBL21756950 0.78 GABRA1 (0.38) LMNATRPA1GABRA1GABRB2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4794015-B2 2011-10-12 JP claimed
JP-4748806-B2 2011-08-17 JP claimed
CN-100416680-C Optical multilayer EASTMAN KODAK CO (JP) 2008-09-03 CN claimed
US-7288296-B2 Multilayer optical compensator, liquid crystal display, and process NITTO DENKO CORPORATION (JP) 2007-10-30 US claimed
US-7250200-B2 Liquid crystal cell with compensator layer and process NITTO DENKO CORPORATION (JP) 2007-07-31 US claimed
US-7236221-B2 Multilayer optical compensation film, liquid crystal display, and process NITTO DENKO CORPORATION (JP) 2007-06-26 US claimed
CN-1961229-A Multilayered optical compensator film with amorphous polymer for liquid crystal displays EASTMAN KODAK CO (US) 2007-05-09 CN claimed
US-7211304-B2 Multilayer optical compensator, liquid crystal display, and process NITTO DENKO CORPORATION (JP) 2007-05-01 US claimed
US-7211316-B2 Optical multilayer NITTO DENKO CORPORATION (JP) 2007-05-01 US claimed
WO-2007001999-A1 MULTILAYERED OPTICAL COMPENSATOR NITTO DENKO CORPORATION (JP) 2007-01-04 WO claimed
US-20050286001-A1 Multilayer optical compensator, liquid crystal display, and process EASTMAN KODAK COMPANY 2005-12-29 US claimed
WO-2005121848-A1 MULTILAYERED OPTICAL COMPENSATOR FILM WITH AMORPHOUS POLYMER FOR LIQUID CRYSTAL DISPLAYS NITTO DENKO CORPORATION (JP) 2005-12-22 WO claimed
WO-2005121880-A1 MULTILAYER OPTICAL COMPENSATION FILM EASTMAN KODAK COMPANY (US) 2005-12-22 WO claimed
US-20050270458-A1 Multilayer optical compensation film, liquid crystal display, and process EASTMAN KODAK COMPANY 2005-12-08 US claimed
US-20050270459-A1 Multilayer optical compensator, liquid crystal display, and process EASTMAN KODAK COMPANY 2005-12-08 US claimed
US-20050237457-A1 Multi-layer compensation film including stretchable barrier layers EASTMAN KODAK COMPANY 2005-10-27 US claimed
WO-2005045820-A1 OPTICAL MULTILAYER EASTMAN KODAK COMPANY (US) 2005-05-19 WO claimed
US-20050089676-A1 Optical multilayer EASTMAN KODAK COMPANY 2005-04-28 US claimed
US-20040264908-A1 Material for attenuating light signals with low reflectance in a fiber optic network FURUKAWA ELECTRIC NORTH AMERICA, INC. 2004-12-30 US claimed
US-20040223103-A1 Liquid crystal cell with compensator layer and process EASTMAN KODAK COMPANY 2004-11-11 US claimed