Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CA4 | P22748 | 3/20 | 0.51 |
| ▸ | CA6 | P23280 | 3/20 | 0.51 |
| ▸ | CA7 | P43166 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4497521 | 1.00 | CA1 (0.51) | CA1CA2CA4CA6CA7 | |
| SCHEMBL4499254 | 1.00 | CA1 (0.51) | CA1CA2CA4CA6CA7 | |
| SCHEMBL562860 | 0.86 | BRD4 (0.53) | CA1CA2CA4CA6CA7 | |
| SCHEMBL563946 | 0.86 | BRD4 (0.53) | CA1CA2CA4CA6CA7 | |
| SCHEMBL4499665 | 0.81 | CA1 (0.51) | CA1CA2CA4CA6CA7 | |
| SCHEMBL4491631 | 0.79 | LMNA (0.56) | CA1CA2CA4CA6CA7 | |
| SCHEMBL4493928 | 0.79 | LMNA (0.58) | CA1CA2CA4CA6CA7 | |
| SCHEMBL27494583 | 0.78 | BRD4 (0.50) | CA1CA2CA4CA6CA7 | |
| SCHEMBL564115 | 0.78 | BRD4 (0.50) | CA1CA2CA4CA6CA7 | |
| SCHEMBL6073829 | 0.78 | LMNA (0.48) | CA1CA2CA4CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473697-B2 | 2-Oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivatives for the treatment of epilepsy and other neurological disorders | UCB S.A. (BE) | 2009-01-06 | — | — | US | disclosed |
| US-7473697-B2 | 2-Oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivatives for the treatment of epilepsy and other neurological disorders | UCB S.A. (BE) | 2009-01-06 | — | — | US | disclosed |
| US-7473697-B2 | 2-Oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivatives for the treatment of epilepsy and other neurological disorders | UCB S.A. (BE) | 2009-01-06 | — | — | US | disclosed |
| US-20060258704-A1 | 2-Oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivatives for the treatment of epilepsy and other neurological disorders | MICHEL PHILIPPE | 2006-11-16 | — | — | US | disclosed |
| US-7087596-B2 | 2-oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivatives for the treatment of epilepsy and other neurological disorders | UCB, S.A. (BE) | 2006-08-08 | — | — | US | disclosed |
| US-20040132717-A1 | 2-Oxo-piperidinyl-and 2-oxo-azepanyl alkanoic acid derivatives for the treatment of epilepsy and other neurological disorders | UCB, S.A. (BE) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040132717-A1 | 2-Oxo-piperidinyl-and 2-oxo-azepanyl alkanoic acid derivatives for the treatment of epilepsy and other neurological disorders | GABRA6, GABRA2, HCAR2 | CA1 723/4885CA2 541/4885CA4 1971/4885 |
| US-20060258704-A1 | 2-Oxo-piperidinyl- and 2-oxo-azepanyl alkanoic acid derivatives for the treatment of epilepsy and other neurological disorders | GABRA6, HCAR2, GABRA2 | CA1 764/4885CA2 539/4885CA4 1945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.